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    NFKB2 nuclear factor kappa B subunit 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 526392, updated on 1-Jan-2025

    Summary

    Official Symbol
    NFKB2provided by VGNC
    Official Full Name
    nuclear factor kappa B subunit 2provided by VGNC
    Primary source
    VGNC:VGNC:32044
    See related
    BGD:BT11574; Ensembl:ENSBTAG00000006017
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    NEW
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    Genomic context

    See NFKB2 in Genome Data Viewer
    Location:
    chromosome: 26
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 26 NC_037353.1 (23018413..23026096)

    Chromosome 26 - NC_037353.1Genomic Context describing neighboring genes Neighboring gene paired like homeodomain 3 Neighboring gene golgi brefeldin A resistant guanine nucleotide exchange factor 1 Neighboring gene uncharacterized LOC132343951 Neighboring gene pleckstrin and Sec7 domain containing Neighboring gene F-box and leucine rich repeat protein 15

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037353.1 Chromosome 26 Reference ARS-UCD2.0 Primary Assembly

    Expression

    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Pathways from PubChem

    General protein information

    Preferred Names
    nuclear factor NF-kappa-B p100 subunit

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102101.1NP_001095571.1  nuclear factor NF-kappa-B p100 subunit

      See identical proteins and their annotated locations for NP_001095571.1

      Status: PROVISIONAL

      Source sequence(s)
      BC151467
      UniProtKB/TrEMBL
      A0AAF6DLJ2, A7MBB7, F6Q9X9
      Related
      ENSBTAP00000007904.7, ENSBTAT00000007904.7
      Conserved Domains (5) summary
      cd07934
      Location:38221
      RHD-n_NFkB2; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor kappa B2 (NF-kappa B2)
      cd08798
      Location:775850
      Death_NFkB2_p100; Death domain of the Nuclear Factor-KappaB2 precursor protein p100
      cd00204
      Location:484621
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01177
      Location:228327
      IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
      sd00045
      Location:600631
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037353.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      23018413..23026096
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024985643.2XP_024841411.1  nuclear factor NF-kappa-B p100 subunit isoform X1

      UniProtKB/TrEMBL
      A0AAA9T421, A0AAF6DLJ2
      Conserved Domains (5) summary
      cd07934
      Location:38221
      RHD-n_NFkB2; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor kappa B2 (NF-kappa B2)
      cd08798
      Location:775850
      Death_NFkB2_p100; Death domain of the Nuclear Factor-KappaB2 precursor protein p100
      cd00204
      Location:484621
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01177
      Location:228327
      IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
      sd00045
      Location:600631
      ANK; ANK repeat [structural motif]
    2. XM_024985647.2XP_024841415.1  nuclear factor NF-kappa-B p100 subunit isoform X2

      UniProtKB/TrEMBL
      A0AAF6DLJ2, A7MBB7, F6Q9X9
      Conserved Domains (5) summary
      cd07934
      Location:38221
      RHD-n_NFkB2; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor kappa B2 (NF-kappa B2)
      cd08798
      Location:775850
      Death_NFkB2_p100; Death domain of the Nuclear Factor-KappaB2 precursor protein p100
      cd00204
      Location:484621
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01177
      Location:228327
      IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
      sd00045
      Location:600631
      ANK; ANK repeat [structural motif]
    3. XM_024985642.2XP_024841410.1  nuclear factor NF-kappa-B p100 subunit isoform X1

      UniProtKB/TrEMBL
      A0AAA9T421, A0AAF6DLJ2
      Related
      ENSBTAP00000091405.1, ENSBTAT00000135447.1
      Conserved Domains (5) summary
      cd07934
      Location:38221
      RHD-n_NFkB2; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor kappa B2 (NF-kappa B2)
      cd08798
      Location:775850
      Death_NFkB2_p100; Death domain of the Nuclear Factor-KappaB2 precursor protein p100
      cd00204
      Location:484621
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01177
      Location:228327
      IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
      sd00045
      Location:600631
      ANK; ANK repeat [structural motif]