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    UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) [ Bos taurus (domestic cattle) ]

    Gene ID: 511801, updated on 1-Jan-2025

    Summary

    Gene symbol
    UBE2D4
    Gene description
    ubiquitin conjugating enzyme E2 D4 (putative)
    See related
    BGD:BT29571; Ensembl:ENSBTAG00000003997
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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    Genomic context

    See UBE2D4 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (341351..366638)

    Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112443523 Neighboring gene mitochondrial ribosomal protein S24 Neighboring gene upregulator of cell proliferation Neighboring gene uncharacterized LOC132343471 Neighboring gene drebrin like Neighboring gene phosphoglycerate mutase 2

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

    Expression

    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin conjugating enzyme activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in protein K11-linked ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in protein K48-linked ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in protein K63-linked ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    ubiquitin-conjugating enzyme E2 D4
    Names
    ubiquitin-conjugating enzyme E2D 4 (putative)
    NP_001069007.1
    XP_005222407.1
    XP_024838365.1
    XP_024838366.1
    XP_024838367.2
    XP_024838369.1
    XP_059735584.1
    XP_059735585.1
    XP_059735586.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075539.2NP_001069007.1  ubiquitin-conjugating enzyme E2 D4

      See identical proteins and their annotated locations for NP_001069007.1

      Status: PROVISIONAL

      Source sequence(s)
      BC109525
      UniProtKB/TrEMBL
      F1MFL6, Q32LL1
      Conserved Domains (2) summary
      COG5078
      Location:1136
      COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
      cl00154
      Location:1137
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      341351..366638
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059879601.1XP_059735584.1  ubiquitin-conjugating enzyme E2 D4 isoform X1

      UniProtKB/TrEMBL
      A0AAA9S092
    2. XM_024982597.2XP_024838365.1  ubiquitin-conjugating enzyme E2 D4 isoform X1

      UniProtKB/TrEMBL
      A0AAA9S092
      Conserved Domains (1) summary
      cl00154
      Location:11151
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    3. XM_059879602.1XP_059735585.1  ubiquitin-conjugating enzyme E2 D4 isoform X5

      UniProtKB/TrEMBL
      A0AAA9S092
    4. XM_005222350.5XP_005222407.1  ubiquitin-conjugating enzyme E2 D4 isoform X3

      See identical proteins and their annotated locations for XP_005222407.1

      UniProtKB/TrEMBL
      A0AAA9S092
      Conserved Domains (1) summary
      cl00154
      Location:1146
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    5. XM_024982598.2XP_024838366.1  ubiquitin-conjugating enzyme E2 D4 isoform X2

      UniProtKB/TrEMBL
      F1MFL6
      Conserved Domains (1) summary
      cl00154
      Location:11142
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    6. XM_024982599.2XP_024838367.2  ubiquitin-conjugating enzyme E2 D4 isoform X4

      UniProtKB/TrEMBL
      A0AAA9S092
    7. XM_059879603.1XP_059735586.1  ubiquitin-conjugating enzyme E2 D4 isoform X6

      UniProtKB/TrEMBL
      A0AAA9S092
      Related
      ENSBTAP00000005220.6, ENSBTAT00000005220.7
    8. XM_024982601.2XP_024838369.1  ubiquitin-conjugating enzyme E2 D4 isoform X7

      Conserved Domains (1) summary
      cl00154
      Location:1109
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

    RNA

    1. XR_003031734.2 RNA Sequence

    2. XR_003031735.2 RNA Sequence