MYBL2 MYB proto-oncogene like 2 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: MYBL2provided by VGNC
Official Full Name: MYB proto-oncogene like 2provided by VGNC
Primary source: VGNC:VGNC:31779
See related: BGD:BT23439; EnsemblRapid:ENSBTAG00070020684
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: BMYB
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	13	NC_037340.1 (72231694..72258247)

Chromosome 13 - NC_037340.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037340.1 Chromosome 13 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

B-Myb represses SMC elastin gene expression and cyclin A plays a role in the developmental regulation of elastin gene expression in the aorta
Title: B-Myb represses elastin gene expression in aortic smooth muscle cells.
B-Myb (MYBL2)repressor function is regulated by cyclin A phosphorylation and sequences within the C-terminal domain.
Title: B-Myb repressor function is regulated by cyclin A phosphorylation and sequences within the C-terminal domain.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Process	Evidence Code	Pubs
involved_in mitotic cell cycle	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: myb-related protein B

Names: v-myb myeloblastosis viral oncogene homolog-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001075448.2 → NP_001068916.1 myb-related protein B

See identical proteins and their annotated locations for NP_001068916.1

Status: PROVISIONAL

Source sequence(s)

BC118123

UniProtKB/TrEMBL

Q17QY0

Related

ENSBTAP00070028004.1, ENSBTAT00070046687.1

Conserved Domains (4) summary

smart00717
Location:83 → 131

SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains

pfam00249
Location:83 → 129

Myb_DNA-binding; Myb-like DNA-binding domain

pfam09316
Location:450 → 606

Cmyb_C; C-myb, C-terminal

pfam13921
Location:34 → 94

Myb_DNA-bind_6; Myb-like DNA-binding domain