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    CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 504632, updated on 1-Jan-2025

    Summary

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    Official Symbol
    CNNM2provided by VGNC
    Official Full Name
    cyclin and CBS domain divalent metal cation transport mediator 2provided by VGNC
    Primary source
    VGNC:VGNC:27511
    See related
    BGD:BT30113; Ensembl:ENSBTAG00000012857
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CNNM2 in Genome Data Viewer
    Location:
    chromosome: 26
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 26 NC_037353.1 (23551257..23735886)

    Chromosome 26 - NC_037353.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450 family 17 subfamily A member 1 Neighboring gene BLOC-1 related complex subunit 7 Neighboring gene arsenite methyltransferase Neighboring gene ubiquitin-ribosomal protein eS31 fusion protein-like Neighboring gene 5'-nucleotidase, cytosolic II Neighboring gene chromosome 26 C6orf52 homolog Neighboring gene internexin neuronal intermediate filament protein alpha

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037353.1 Chromosome 26 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables magnesium ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular manganese ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in magnesium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    metal transporter CNNM2
    Names
    cyclin M2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191172.1 → NP_001178101.1  metal transporter CNNM2

      See identical proteins and their annotated locations for NP_001178101.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000026
      UniProtKB/TrEMBL
      E1BIL3
      Related
      ENSBTAP00000017085.5, ENSBTAT00000017085.7
      Conserved Domains (2) summary
      cd04590
      Location:470 → 575
      CBS_pair_CorC_HlyC_assoc; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in ...
      pfam01595
      Location:257 → 431
      DUF21; Domain of unknown function DUF21

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037353.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      23551257..23735886
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005225471.5 → XP_005225528.1  metal transporter CNNM2 isoform X1

      See identical proteins and their annotated locations for XP_005225528.1

      UniProtKB/TrEMBL
      A0A3Q1LRB9
      Related
      ENSBTAP00000059542.1, ENSBTAT00000070051.2
      Conserved Domains (2) summary
      cd04590
      Location:470 → 575
      CBS_pair_CorC_HlyC_assoc; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in ...
      pfam01595
      Location:257 → 431
      DUF21; Domain of unknown function DUF21

    2. XM_010819836.4 → XP_010818138.1  metal transporter CNNM2 isoform X2

      See identical proteins and their annotated locations for XP_010818138.1

      Conserved Domains (2) summary
      pfam01595
      Location:257 → 431
      DUF21; Domain of unknown function DUF21
      cl15354
      Location:470 → 544
      CBS_pair; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...

    RNA

    1. XR_003032723.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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