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    RNF216 ring finger protein 216 [ Bos taurus (domestic cattle) ]

    Gene ID: 534455, updated on 1-Jan-2025

    Summary

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    Official Symbol
    RNF216provided by VGNC
    Official Full Name
    ring finger protein 216provided by VGNC
    Primary source
    VGNC:VGNC:34053
    See related
    BGD:BT14707; Ensembl:ENSBTAG00000017175
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    TRIAD3
    Orthologs
    human mouse all
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    Genomic context

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    See RNF216 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (38616501..38737195)

    Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 182 Neighboring gene olfactory receptor family 10 subfamily AH member 1 Neighboring gene transfer RNA glycine (anticodon UCC) Neighboring gene fascin actin-bundling protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein linear polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of LUBAC complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase RNF216
    NP_001180187.1
    XP_005225226.1
    XP_059737366.1
    XP_059737367.1
    XP_059737368.1
    XP_059737369.1
    XP_059737370.1
    XP_059737371.1
    XP_059737372.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001193258.1 → NP_001180187.1  E3 ubiquitin-protein ligase RNF216

      See identical proteins and their annotated locations for NP_001180187.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000025
      UniProtKB/TrEMBL
      A0AAA9T7A0
      Related
      ENSBTAP00000092620.1, ENSBTAT00000124343.1
      Conserved Domains (1) summary
      cd16630
      Location:516 → 572
      RING-HC_RBR_RNF216; RING finger, HC subclass, found in RING finger protein 216 (RNF216) and similar proteins

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      38616501..38737195
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059881385.1 → XP_059737368.1  E3 ubiquitin-protein ligase RNF216 isoform X1

      UniProtKB/TrEMBL
      A0AAA9T7A0, E1BHM7

    2. XM_059881386.1 → XP_059737369.1  E3 ubiquitin-protein ligase RNF216 isoform X1

      UniProtKB/TrEMBL
      A0AAA9T7A0, E1BHM7

    3. XM_059881384.1 → XP_059737367.1  E3 ubiquitin-protein ligase RNF216 isoform X1

      UniProtKB/TrEMBL
      A0AAA9T7A0, E1BHM7

    4. XM_059881387.1 → XP_059737370.1  E3 ubiquitin-protein ligase RNF216 isoform X2

      UniProtKB/TrEMBL
      A0AAA9T7A0

    5. XM_059881383.1 → XP_059737366.1  E3 ubiquitin-protein ligase RNF216 isoform X1

      UniProtKB/TrEMBL
      A0AAA9T7A0, E1BHM7

    6. XM_005225169.5 → XP_005225226.1  E3 ubiquitin-protein ligase RNF216 isoform X1

      See identical proteins and their annotated locations for XP_005225226.1

      UniProtKB/TrEMBL
      A0AAA9T7A0, E1BHM7
      Related
      ENSBTAP00000022820.6, ENSBTAT00000022820.7
      Conserved Domains (1) summary
      cd16630
      Location:573 → 629
      RING-HC_RBR_RNF216; RING finger, HC subclass, found in RING finger protein 216 (RNF216) and similar proteins

    7. XM_059881389.1 → XP_059737372.1  E3 ubiquitin-protein ligase RNF216 isoform X4

      UniProtKB/TrEMBL
      A0AAA9TNX3
      Related
      ENSBTAP00000098031.1, ENSBTAT00000120364.1

    8. XM_059881388.1 → XP_059737371.1  E3 ubiquitin-protein ligase RNF216 isoform X3

      UniProtKB/TrEMBL
      A0AAA9TNX3
    Nucleotide Protein Strain
    Heading Accession and Version

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