U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    MBD1 methyl-CpG binding domain protein 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 540558, updated on 1-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    MBD1provided by VGNC
    Official Full Name
    methyl-CpG binding domain protein 1provided by VGNC
    Primary source
    VGNC:VGNC:31273
    See related
    BGD:BT22679; Ensembl:ENSBTAG00000003801
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See MBD1 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 24 NC_037351.1 (49898769..49915949, complement)

    Chromosome 24 - NC_037351.1Genomic Context describing neighboring genes Neighboring gene myosin VB Neighboring gene cofilin-1-like Neighboring gene cilia and flagella associated protein 53 Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene CXXC finger protein 1 Neighboring gene spindle and kinetochore associated complex subunit 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037351.1 Chromosome 24 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Unexpected cross-species contamination in genome sequencing projects. Merchant S, et al. PeerJ, 2014. PMID 25426337, Free PMC Article
    2. The genome sequence of taurine cattle: a window to ruminant biology and evolution. Bovine Genome Sequencing and Analysis Consortium, et al. Science, 2009 Apr 24. PMID 19390049, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC133916

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables methyl-CpG binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA methylation-dependent constitutive heterochromatin formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    methyl-CpG-binding domain protein 1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001046481.2 → NP_001039946.1  methyl-CpG-binding domain protein 1

      See identical proteins and their annotated locations for NP_001039946.1

      Status: PROVISIONAL

      Source sequence(s)
      BC112458
      UniProtKB/TrEMBL
      A0A3Q1MW55, Q2KIY8
      Conserved Domains (4) summary
      smart00391
      Location:3 → 76
      MBD; Methyl-CpG binding domain
      pfam02008
      Location:357 → 403
      zf-CXXC; CXXC zinc finger domain
      cl26386
      Location:413 → 594
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
      cl28054
      Location:28 → 151
      Pox_Ag35; Pox virus Ag35 surface protein

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037351.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      49898769..49915949 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059880972.1 → XP_059736955.1  methyl-CpG-binding domain protein 1 isoform X30

      UniProtKB/TrEMBL
      A0A3Q1LIQ1

    2. XM_010818929.3 → XP_010817231.1  methyl-CpG-binding domain protein 1 isoform X27

      UniProtKB/TrEMBL
      A0A3Q1LIQ1, A0AAA9SIL1
      Related
      ENSBTAP00000083596.1, ENSBTAT00000125562.1
      Conserved Domains (4) summary
      smart00391
      Location:3 → 76
      MBD; Methyl-CpG binding domain
      pfam02008
      Location:309 → 355
      zf-CXXC; CXXC zinc finger domain
      cl27975
      Location:363 → 571
      EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)
      cl28054
      Location:28 → 151
      Pox_Ag35; Pox virus Ag35 surface protein

    3. XM_005224260.4 → XP_005224317.1  methyl-CpG-binding domain protein 1 isoform X34

      UniProtKB/TrEMBL
      A0A3Q1LIQ1
      Conserved Domains (4) summary
      smart00391
      Location:3 → 76
      MBD; Methyl-CpG binding domain
      pfam02008
      Location:309 → 355
      zf-CXXC; CXXC zinc finger domain
      cl27975
      Location:363 → 494
      EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)
      cl28054
      Location:28 → 151
      Pox_Ag35; Pox virus Ag35 surface protein

    4. XM_059880969.1 → XP_059736952.1  methyl-CpG-binding domain protein 1 isoform X24

      UniProtKB/TrEMBL
      A0A3Q1LIQ1

    5. XM_059880971.1 → XP_059736954.1  methyl-CpG-binding domain protein 1 isoform X29

      UniProtKB/TrEMBL
      A0A3Q1LIQ1

    6. XM_024984378.2 → XP_024840146.1  methyl-CpG-binding domain protein 1 isoform X26

      UniProtKB/TrEMBL
      A0A3Q1MW55
      Conserved Domains (4) summary
      smart00391
      Location:3 → 76
      MBD; Methyl-CpG binding domain
      pfam02008
      Location:331 → 377
      zf-CXXC; CXXC zinc finger domain
      cl26386
      Location:387 → 556
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
      cl28054
      Location:28 → 151
      Pox_Ag35; Pox virus Ag35 surface protein

    7. XM_059880963.1 → XP_059736946.1  methyl-CpG-binding domain protein 1 isoform X16

      UniProtKB/TrEMBL
      A0A3Q1MW55

    8. XM_059880950.1 → XP_059736933.1  methyl-CpG-binding domain protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A3Q1MW55

    9. XM_024984376.2 → XP_024840144.1  methyl-CpG-binding domain protein 1 isoform X21

      UniProtKB/TrEMBL
      A0A3Q1MW55
      Conserved Domains (4) summary
      smart00391
      Location:3 → 76
      MBD; Methyl-CpG binding domain
      pfam02008
      Location:331 → 377
      zf-CXXC; CXXC zinc finger domain
      cl26386
      Location:387 → 568
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
      cl28054
      Location:28 → 151
      Pox_Ag35; Pox virus Ag35 surface protein

    10. XM_010818930.3 → XP_010817232.1  methyl-CpG-binding domain protein 1 isoform X31

      UniProtKB/TrEMBL
      A0A3Q1MW55
      Conserved Domains (4) summary
      smart00391
      Location:3 → 76
      MBD; Methyl-CpG binding domain
      pfam02008
      Location:332 → 378
      zf-CXXC; CXXC zinc finger domain
      cl27975
      Location:386 → 517
      EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)
      cl28054
      Location:28 → 151
      Pox_Ag35; Pox virus Ag35 surface protein

    11. XM_059880965.1 → XP_059736948.1  methyl-CpG-binding domain protein 1 isoform X18

      UniProtKB/TrEMBL
      A0A3Q1MW55

    12. XM_010818931.3 → XP_010817233.1  methyl-CpG-binding domain protein 1 isoform X33

      UniProtKB/TrEMBL
      A0A3Q1MW55
      Conserved Domains (4) summary
      smart00391
      Location:3 → 76
      MBD; Methyl-CpG binding domain
      pfam02008
      Location:332 → 378
      zf-CXXC; CXXC zinc finger domain
      cl27975
      Location:386 → 517
      EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)
      cl28054
      Location:28 → 151
      Pox_Ag35; Pox virus Ag35 surface protein

    13. XM_059880967.1 → XP_059736950.1  methyl-CpG-binding domain protein 1 isoform X22

      UniProtKB/TrEMBL
      A0A3Q1MW55

    14. XM_059880951.1 → XP_059736934.1  methyl-CpG-binding domain protein 1 isoform X6

      UniProtKB/TrEMBL
      A0A3Q1MW55

    15. XM_024984377.2 → XP_024840145.1  methyl-CpG-binding domain protein 1 isoform X25

      UniProtKB/TrEMBL
      A0A3Q1MW55
      Conserved Domains (4) summary
      smart00391
      Location:3 → 76
      MBD; Methyl-CpG binding domain
      pfam02008
      Location:332 → 378
      zf-CXXC; CXXC zinc finger domain
      cl26386
      Location:388 → 557
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
      cl28054
      Location:28 → 151
      Pox_Ag35; Pox virus Ag35 surface protein

    16. XM_059880959.1 → XP_059736942.1  methyl-CpG-binding domain protein 1 isoform X12

      UniProtKB/TrEMBL
      A0A3Q1MW55
      Related
      ENSBTAP00000059543.2, ENSBTAT00000080481.2

    17. XM_059880962.1 → XP_059736945.1  methyl-CpG-binding domain protein 1 isoform X15

      UniProtKB/TrEMBL
      A0A3Q1MW55

    18. XM_005224252.4 → XP_005224309.1  methyl-CpG-binding domain protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A3Q1MW55
      Conserved Domains (4) summary
      smart00391
      Location:3 → 76
      MBD; Methyl-CpG binding domain
      pfam02008
      Location:332 → 378
      zf-CXXC; CXXC zinc finger domain
      cl26386
      Location:388 → 569
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
      cl28054
      Location:28 → 151
      Pox_Ag35; Pox virus Ag35 surface protein

    19. XM_005224257.4 → XP_005224314.1  methyl-CpG-binding domain protein 1 isoform X20

      UniProtKB/TrEMBL
      A0A3Q1MW55
      Conserved Domains (4) summary
      smart00391
      Location:3 → 76
      MBD; Methyl-CpG binding domain
      pfam02008
      Location:332 → 378
      zf-CXXC; CXXC zinc finger domain
      cl26386
      Location:388 → 569
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
      cl28054
      Location:28 → 151
      Pox_Ag35; Pox virus Ag35 surface protein

    20. XM_059880964.1 → XP_059736947.1  methyl-CpG-binding domain protein 1 isoform X17

      UniProtKB/TrEMBL
      A0A3Q1MW55

    21. XM_059880973.1 → XP_059736956.1  methyl-CpG-binding domain protein 1 isoform X32

      UniProtKB/TrEMBL
      A0A3Q1LIQ1

    22. XM_059880949.1 → XP_059736932.1  methyl-CpG-binding domain protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1MW55

    23. XM_059880966.1 → XP_059736949.1  methyl-CpG-binding domain protein 1 isoform X19

      UniProtKB/TrEMBL
      A0A3Q1LIQ1

    24. XM_059880961.1 → XP_059736944.1  methyl-CpG-binding domain protein 1 isoform X14

      UniProtKB/TrEMBL
      A0A3Q1MW55

    25. XM_059880957.1 → XP_059736940.1  methyl-CpG-binding domain protein 1 isoform X10

      UniProtKB/TrEMBL
      A0A3Q1MW55

    26. XM_059880968.1 → XP_059736951.1  methyl-CpG-binding domain protein 1 isoform X23

      UniProtKB/TrEMBL
      A0A3Q1MW55

    27. XM_059880953.1 → XP_059736936.1  methyl-CpG-binding domain protein 1 isoform X8

      UniProtKB/TrEMBL
      A0A3Q1MW55

    28. XM_059880970.1 → XP_059736953.1  methyl-CpG-binding domain protein 1 isoform X28

      UniProtKB/TrEMBL
      A0A3Q1MW55

    29. XM_059880958.1 → XP_059736941.1  methyl-CpG-binding domain protein 1 isoform X11

      UniProtKB/TrEMBL
      A0A3Q1MW55

    30. XM_024984375.2 → XP_024840143.1  methyl-CpG-binding domain protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MW55
      Conserved Domains (4) summary
      smart00391
      Location:3 → 76
      MBD; Methyl-CpG binding domain
      pfam02008
      Location:357 → 403
      zf-CXXC; CXXC zinc finger domain
      cl26386
      Location:413 → 582
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
      cl28054
      Location:28 → 151
      Pox_Ag35; Pox virus Ag35 surface protein

    31. XM_059880960.1 → XP_059736943.1  methyl-CpG-binding domain protein 1 isoform X13

      UniProtKB/TrEMBL
      A0A3Q1MW55

    32. XM_059880952.1 → XP_059736935.1  methyl-CpG-binding domain protein 1 isoform X7

      UniProtKB/TrEMBL
      A0A3Q1MW55

    33. XM_024984374.2 → XP_024840142.1  methyl-CpG-binding domain protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MRI0, A0A3Q1MW55
      Related
      ENSBTAP00000074393.2, ENSBTAT00000086116.2
      Conserved Domains (4) summary
      smart00391
      Location:3 → 76
      MBD; Methyl-CpG binding domain
      pfam02008
      Location:357 → 403
      zf-CXXC; CXXC zinc finger domain
      cl26386
      Location:413 → 594
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
      cl28054
      Location:28 → 151
      Pox_Ag35; Pox virus Ag35 surface protein

    34. XM_005224253.4 → XP_005224310.1  methyl-CpG-binding domain protein 1 isoform X9

      UniProtKB/TrEMBL
      A0A3Q1LUL8, A0A3Q1MW55
      Conserved Domains (4) summary
      smart00391
      Location:3 → 76
      MBD; Methyl-CpG binding domain
      pfam02008
      Location:357 → 403
      zf-CXXC; CXXC zinc finger domain
      cl26386
      Location:413 → 594
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
      cl28054
      Location:28 → 151
      Pox_Ag35; Pox virus Ag35 surface protein

    35. XM_059880956.1 → XP_059736939.1  methyl-CpG-binding domain protein 1 isoform X9

      UniProtKB/TrEMBL
      A0A3Q1LUL8, A0A3Q1MW55
      Related
      ENSBTAP00000060840.1, ENSBTAT00000079863.2

    36. XM_059880955.1 → XP_059736938.1  methyl-CpG-binding domain protein 1 isoform X9

      UniProtKB/TrEMBL
      A0A3Q1LUL8, A0A3Q1MW55

    37. XM_059880954.1 → XP_059736937.1  methyl-CpG-binding domain protein 1 isoform X9

      UniProtKB/TrEMBL
      A0A3Q1LUL8, A0A3Q1MW55
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials