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    ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit [ Bos taurus (domestic cattle) ]

    Gene ID: 615637, updated on 1-Jan-2025

    Summary

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    Official Symbol
    ERCC1provided by VGNC
    Official Full Name
    ERCC excision repair 1, endonuclease non-catalytic subunitprovided by VGNC
    Primary source
    VGNC:VGNC:28568
    See related
    BGD:BT10330; Ensembl:ENSBTAG00000017355
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ERCC1 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (53024536..53055873, complement)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene kinesin light chain 3 Neighboring gene ERCC excision repair 2, TFIIH core complex helicase subunit Neighboring gene protein phosphatase 1 regulatory subunit 13 like Neighboring gene RNA polymerase I subunit G Neighboring gene uncharacterized LOC112442336 Neighboring gene transfer RNA opal suppressor (anticodon UCA) Neighboring gene FosB proto-oncogene, AP-1 transcription factor subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC140762

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables damaged DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables single-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in UV-damage excision repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic recombination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ERCC4-ERCC1 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of nucleotide-excision repair factor 1 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA excision repair protein ERCC-1
    Names
    excision repair cross-complementing 1
    excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076385.2 → NP_001069853.1  DNA excision repair protein ERCC-1

      See identical proteins and their annotated locations for NP_001069853.1

      Status: PROVISIONAL

      Source sequence(s)
      BC116163
      UniProtKB/Swiss-Prot
      Q1LZ75
      UniProtKB/TrEMBL
      A0AAF6Z4C8
      Related
      ENSBTAP00000023078.5, ENSBTAT00000023078.6
      Conserved Domains (2) summary
      pfam03834
      Location:96 → 209
      Rad10; Binding domain of DNA repair protein Ercc1 (rad10/Swi10)
      cl27456
      Location:247 → 287
      UvrC; Excinuclease UvrABC, nuclease subunit [Replication, recombination and repair]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      53024536..53055873 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059876912.1 → XP_059732895.1  DNA excision repair protein ERCC-1 isoform X1

      UniProtKB/TrEMBL
      A0AAA9RWS8, A0AAA9TCQ6
      Related
      ENSBTAP00000093914.1, ENSBTAT00000100091.1

    2. XM_005219336.5 → XP_005219393.1  DNA excision repair protein ERCC-1 isoform X3

      See identical proteins and their annotated locations for XP_005219393.1

      UniProtKB/Swiss-Prot
      Q1LZ75
      UniProtKB/TrEMBL
      A0AAF6Z4C8
      Conserved Domains (2) summary
      pfam03834
      Location:96 → 209
      Rad10; Binding domain of DNA repair protein Ercc1 (rad10/Swi10)
      cl27456
      Location:247 → 287
      UvrC; Excinuclease UvrABC, nuclease subunit [Replication, recombination and repair]

    3. XM_010815082.4 → XP_010813384.1  DNA excision repair protein ERCC-1 isoform X3

      See identical proteins and their annotated locations for XP_010813384.1

      UniProtKB/Swiss-Prot
      Q1LZ75
      UniProtKB/TrEMBL
      A0AAF6Z4C8
      Conserved Domains (2) summary
      pfam03834
      Location:96 → 209
      Rad10; Binding domain of DNA repair protein Ercc1 (rad10/Swi10)
      cl27456
      Location:247 → 287
      UvrC; Excinuclease UvrABC, nuclease subunit [Replication, recombination and repair]

    4. XM_005219335.4 → XP_005219392.1  DNA excision repair protein ERCC-1 isoform X2

      UniProtKB/TrEMBL
      A0AAA9RXX4, A0AAF6Z4C8
      Related
      ENSBTAP00000074662.1, ENSBTAT00000133021.1
      Conserved Domains (2) summary
      pfam03834
      Location:108 → 221
      Rad10; Binding domain of DNA repair protein Ercc1 (rad10/Swi10)
      pfam14520
      Location:247 → 293
      HHH_5; Helix-hairpin-helix domain

    5. XM_005219337.4 → XP_005219394.1  DNA excision repair protein ERCC-1 isoform X3

      See identical proteins and their annotated locations for XP_005219394.1

      UniProtKB/Swiss-Prot
      Q1LZ75
      UniProtKB/TrEMBL
      A0AAF6Z4C8
      Conserved Domains (2) summary
      pfam03834
      Location:96 → 209
      Rad10; Binding domain of DNA repair protein Ercc1 (rad10/Swi10)
      cl27456
      Location:247 → 287
      UvrC; Excinuclease UvrABC, nuclease subunit [Replication, recombination and repair]

    6. XM_024978499.2 → XP_024834267.1  DNA excision repair protein ERCC-1 isoform X3

      UniProtKB/Swiss-Prot
      Q1LZ75
      UniProtKB/TrEMBL
      A0AAF6Z4C8
      Conserved Domains (2) summary
      pfam03834
      Location:96 → 209
      Rad10; Binding domain of DNA repair protein Ercc1 (rad10/Swi10)
      cl27456
      Location:247 → 287
      UvrC; Excinuclease UvrABC, nuclease subunit [Replication, recombination and repair]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1LZ75.1 GenPept UniProtKB/Swiss-Prot:Q1LZ75

    Gene LinkOut

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