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    RYR3 ryanodine receptor 3 [ Homo sapiens (human) ]

    Gene ID: 6263, updated on 10-Dec-2024

    Summary

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    Official Symbol
    RYR3provided by HGNC
    Official Full Name
    ryanodine receptor 3provided by HGNC
    Primary source
    HGNC:HGNC:10485
    See related
    Ensembl:ENSG00000198838 MIM:180903; AllianceGenome:HGNC:10485
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    RYR-3; CMYO20; CMYP20
    Summary
    The protein encoded by this gene is a ryanodine receptor, which functions to release calcium from intracellular storage for use in many cellular processes. For example, the encoded protein is involved in skeletal muscle contraction by releasing calcium from the sarcoplasmic reticulum followed by depolarization of T-tubules. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
    Expression
    Broad expression in brain (RPKM 1.5), endometrium (RPKM 1.4) and 19 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See RYR3 in Genome Data Viewer
    Location:
    15q13.3-q14
    Exon count:
    107
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (33310967..33866102)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (31107439..31663747)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (33603168..34158303)

    Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene ReSE screen-validated silencer GRCh37_chr15:33530426-33530595 Neighboring gene transmembrane and coiled-coil domains 5B (pseudogene) Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:33603389-33603900 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:33603901-33604410 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6271 Neighboring gene NANOG hESC enhancer GRCh37_chr15:33620309-33620820 Neighboring gene RYR3 divergent transcript Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr15:33837506-33838705 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:33851407-33852197 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr15:33904937-33905438 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:33924098-33924317 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr15:34012814-34014013 Neighboring gene NANOG hESC enhancer GRCh37_chr15:34030252-34030792 Neighboring gene complement C1q binding protein pseudogene 3 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:34050593-34051255 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_39317 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr15:34145183-34146382 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr15:34150522-34151721 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9170 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9171 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9172 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:34208100-34208650 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6272 Neighboring gene apoptosis and caspase activation inhibitor Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:34277417-34277940 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:34280047-34280546 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:34314668-34315168 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:34315169-34315669 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6273 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6274 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6275 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6276 Neighboring gene cholinergic receptor muscarinic 5 Neighboring gene MPRA-validated peak2290 silencer Neighboring gene ribosomal protein L32 pseudogene 2 Neighboring gene ER membrane protein complex subunit 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Genomic Characteristics of Gender Dysphoria Patients and Identification of Rare Mutations in RYR3 Gene. Yang F, et al. Sci Rep, 2017 Aug 21. PMID 28827537, Free PMC Article
    2. RYR3 gene polymorphisms and cardiovascular disease outcomes in the context of antihypertensive treatment. Lynch AI, et al. Pharmacogenomics J, 2013 Aug. PMID 22664477, Free PMC Article
    3. Replication of RYR3 gene polymorphism association with cIMT among HIV-infected whites. Shrestha S, et al. AIDS, 2012 Jul 31. PMID 22627881, Free PMC Article
    4. Glutamate drugs and pharmacogenetics of OCD: a pathway-based exploratory approach. Grados MA, et al. Expert Opin Drug Discov, 2013 Dec. PMID 24147578
    5. RyR3 in situ regulation by Ca(2+) and quercetin and the RyR3-mediated Ca(2+) release flux in intact Jurkat cells. Baran I, et al. Arch Biochem Biophys, 2013 Dec. PMID 24211435

    See all (66) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The genomic and clinical landscape of fetal akinesia.
      Title: The genomic and clinical landscape of fetal akinesia.
    2. RYR3 variants are associated with risk of and age of onset for hypertension, diabetes, and Alzheimer disease.
      Title: Polymorphisms Within RYR3 Gene Are Associated With Risk and Age at Onset of Hypertension, Diabetes, and Alzheimer's Disease.
    3. The Ryr Ca2+ release channel is central to cytoplasmic Ca2+ signalling in skeletal muscle, the heart, and many other tissues, playing a vital role in muscular contraction.
      Title: Altered ryanodine receptor gene expression in Hirschsprung's disease.
    4. Mutations in RYR3 Gene is associated with Gender Dysphoria.
      Title: Genomic Characteristics of Gender Dysphoria Patients and Identification of Rare Mutations in RYR3 Gene.
    5. a genome-wide linkage scan and regional association fine-mapping identified variants in the RYR3 gene as a quantitative trail locus for plasma adiponectin levels in Chinese population
      Title: Genome-wide linkage analysis and regional fine mapping identified variants in the RYR3 gene as a novel quantitative trait locus for circulating adiponectin in Chinese population.
    6. Studies indicate that the ryanodine receptors (RyRs: RyR1, RyR2, RyR3) and inositol 1,4,5-trisphosphate receptors (IP3Rs: IP3R1, IP3R2, IP3R3) are the major Ca(2+) release channels (CRCs) on the endo/sarcoplasmic reticulum (ER/SR).
      Title: Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.
    7. Data show that the common variant single-nucleotide polymorphism rs2229116 of the ryanodine receptor 3 gene (RYR3) was significantly associated with carotid intima-media thickness (cIMT).
      Title: Deep sequencing of RYR3 gene identifies rare and common variants associated with increased carotid intima-media thickness (cIMT) in HIV-infected individuals.
    8. SNPs within the RYR3 region were associated with subclinical atherosclerosis among HIV-infected women. Allelic heterogeneity observed across the three races suggests that the contribution of the RYR3 gene to CCA cIMT is complex.
      Title: RYR3 gene variants in subclinical atherosclerosis among HIV-infected women in the Women's Interagency HIV Study (WIHS).
    9. rs877087 and rs2229116 of RYR3 gene are associated with atherosclerosis severity in Japanese.
      Title: Association of the RYR3 gene polymorphisms with atherosclerosis in elderly Japanese population.
    10. a genetic interaction between the RYR3 and CACNA1C genes explained variance in amyloid deposition above and beyond other major known risk factors for late-onset Alzheimer's disease
      Title: Genetic interactions found between calcium channel genes modulate amyloid load measured by positron emission tomography.
    Submit: New GeneRIF Correction See all GeneRIFs (32)

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Associated conditions

    Description Tests
    Congenital myopathy 20
    MedGen: C5830393 OMIM: 620310 GeneReviews: Not available
    		Compare labs

    EBI GWAS Catalog

    Description
    A genome-wide association study of carotid atherosclerosis in HIV-infected men.
    EBI GWAS Catalog
    Genome-wide association study of chronic periodontitis in a general German population.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    HIV-1 interactions

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    Protein interactions

    Protein Gene Interaction Pubs
    Tat tat HIV-1 Tat activates RyRs via a calcium- and calpain-mediated mechanism that upregulates DAT trafficking to the PM PubMed
    tat Neurons exposed to HIV-1 Tat induces calcium loss from the endoplasmic reticulum via ryanodine receptor (RyR) and increases the phosphorylated levels of PERK, eIF2a, and XBP1 PubMed
    tat RYR3 gene regulated by HIV-1 Tat is associated with common and internal carotid intima-media thicknesses (cIMT) in HARRT-treated HIV-infected persons PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calcium-induced calcium release activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables intracellularly gated calcium channel activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables ryanodine-sensitive calcium-release channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ryanodine-sensitive calcium-release channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables ryanodine-sensitive calcium-release channel activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in calcium ion transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in calcium-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cellular response to ATP ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in cellular response to caffeine ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in cellular response to calcium ion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in cellular response to magnesium ion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in intracellular calcium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein homotetramerization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in release of sequestered calcium ion into cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in release of sequestered calcium ion into cytosol by sarcoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in striated muscle contraction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Z disc IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of calcium channel complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in sarcolemma IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in sarcoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in sarcoplasmic reticulum membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in sarcoplasmic reticulum membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in sarcoplasmic reticulum membrane TAS
    Traceable Author Statement
    more info
    		  
    is_active_in smooth endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ryanodine receptor 3
    Names
    brain ryanodine receptor-calcium release channel
    brain-type ryanodine receptor
    type 3 ryanodine receptor

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_047076.1 RefSeqGene

      Range
      5185..560320
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001036.6 → NP_001027.3  ryanodine receptor 3 isoform 1

      See identical proteins and their annotated locations for NP_001027.3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC010809, AC011938, AC055874, AC067793, AC087638
      Consensus CDS
      CCDS45210.1
      UniProtKB/Swiss-Prot
      O15175, Q15412, Q15413
      UniProtKB/TrEMBL
      A0A0X1KG73
      Related
      ENSP00000489262.1, ENST00000634891.2
      Conserved Domains (12) summary
      smart00472
      Location:275 → 368
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      cd12877
      Location:641 → 792
      SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
      cd12878
      Location:1072 → 1204
      SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
      pfam00520
      Location:4621 → 4781
      Ion_trans; Ion transport protein
      pfam01365
      Location:442 → 621
      RYDR_ITPR; RIH domain
      pfam02026
      Location:849 → 937
      RyR; RyR domain
      pfam02815
      Location:216 → 397
      MIR; MIR domain
      pfam06459
      Location:4234 → 4504
      RR_TM4-6; Ryanodine Receptor TM 4-6
      pfam08454
      Location:3731 → 3844
      RIH_assoc; RyR and IP3R Homology associated
      pfam13833
      Location:3935 → 3983
      EF-hand_8; EF-hand domain pair
      cd12879
      Location:1324 → 1462
      SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
      cl19745
      Location:12 → 207
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    2. NM_001243996.4 → NP_001230925.1  ryanodine receptor 3 isoform 2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region compared to variant 1. The resulting isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AB001025, AC011938, AC087638, AJ001515
      Consensus CDS
      CCDS58351.1
      UniProtKB/TrEMBL
      A0A0X1KG73
      Related
      ENSP00000399610.3, ENST00000415757.7
      Conserved Domains (12) summary
      smart00472
      Location:275 → 368
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      cd12877
      Location:641 → 792
      SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
      cd12878
      Location:1072 → 1204
      SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
      pfam00520
      Location:4616 → 4776
      Ion_trans; Ion transport protein
      pfam01365
      Location:442 → 621
      RYDR_ITPR; RIH domain
      pfam02026
      Location:849 → 937
      RyR; RyR domain
      pfam02815
      Location:216 → 397
      MIR; MIR domain
      pfam06459
      Location:4229 → 4499
      RR_TM4-6; Ryanodine Receptor TM 4-6
      pfam08454
      Location:3726 → 3839
      RIH_assoc; RyR and IP3R Homology associated
      pfam13833
      Location:3930 → 3978
      EF-hand_8; EF-hand domain pair
      cd12879
      Location:1324 → 1462
      SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
      cl19745
      Location:12 → 207
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

      Range
      33310967..33866102
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047432931.1 → XP_047288887.1  ryanodine receptor 3 isoform X10

      UniProtKB/TrEMBL
      A0A0X1KG73

    2. XM_017022468.2 → XP_016877957.1  ryanodine receptor 3 isoform X1

      UniProtKB/TrEMBL
      A0A0X1KG73

    3. XM_017022475.2 → XP_016877964.1  ryanodine receptor 3 isoform X11

      UniProtKB/TrEMBL
      A0A0X1KG73

    4. XM_017022473.2 → XP_016877962.1  ryanodine receptor 3 isoform X7

      UniProtKB/TrEMBL
      A0A0X1KG73

    5. XM_047432932.1 → XP_047288888.1  ryanodine receptor 3 isoform X12

      UniProtKB/TrEMBL
      A0A0X1KG73

    6. XM_017022469.2 → XP_016877958.1  ryanodine receptor 3 isoform X2

      UniProtKB/TrEMBL
      A0A0X1KG73

    7. XM_011521880.3 → XP_011520182.1  ryanodine receptor 3 isoform X8

      UniProtKB/TrEMBL
      A0A0U1RRH1, A0A0X1KG73
      Related
      ENSP00000489529.1, ENST00000634418.1
      Conserved Domains (12) summary
      smart00472
      Location:275 → 368
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      cd12877
      Location:641 → 792
      SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
      cd12878
      Location:1072 → 1204
      SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
      pfam00520
      Location:4610 → 4770
      Ion_trans; Ion transport protein
      pfam01365
      Location:442 → 621
      RYDR_ITPR; RIH domain
      pfam02026
      Location:849 → 937
      RyR; RyR domain
      pfam02815
      Location:216 → 397
      MIR; MIR domain
      pfam06459
      Location:4223 → 4493
      RR_TM4-6; Ryanodine Receptor TM 4-6
      pfam08454
      Location:3720 → 3833
      RIH_assoc; RyR and IP3R Homology associated
      pfam13833
      Location:3924 → 3972
      EF-hand_8; EF-hand domain pair
      cd12879
      Location:1324 → 1462
      SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
      cl19745
      Location:12 → 207
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    8. XM_017022472.2 → XP_016877961.1  ryanodine receptor 3 isoform X5

      UniProtKB/TrEMBL
      A0A0X1KG73

    9. XM_017022471.2 → XP_016877960.1  ryanodine receptor 3 isoform X4

      UniProtKB/TrEMBL
      A0A0X1KG73

    10. XM_024450015.2 → XP_024305783.1  ryanodine receptor 3 isoform X6

      UniProtKB/TrEMBL
      A0A0X1KG73
      Conserved Domains (11) summary
      cd12877
      Location:641 → 792
      SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
      cd12878
      Location:1072 → 1204
      SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
      cd12879
      Location:1318 → 1461
      SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
      pfam00520
      Location:4615 → 4775
      Ion_trans; Ion transport protein
      pfam01365
      Location:440 → 621
      RYDR_ITPR; RIH domain
      pfam02026
      Location:849 → 937
      RyR; RyR domain
      pfam02815
      Location:216 → 397
      MIR; MIR domain
      pfam06459
      Location:4228 → 4498
      RR_TM4-6; Ryanodine Receptor TM 4-6
      pfam08454
      Location:3725 → 3838
      RIH_assoc; RyR and IP3R Homology associated
      pfam13499
      Location:3922 → 3977
      EF-hand_7; EF-hand domain pair
      cl19745
      Location:12 → 207
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    11. XM_024450016.2 → XP_024305784.1  ryanodine receptor 3 isoform X16

      UniProtKB/TrEMBL
      A0A0X1KG73
      Conserved Domains (11) summary
      cd12877
      Location:641 → 792
      SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
      cd12878
      Location:1072 → 1204
      SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
      cd12879
      Location:1318 → 1461
      SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
      pfam00520
      Location:4614 → 4774
      Ion_trans; Ion transport protein
      pfam01365
      Location:440 → 621
      RYDR_ITPR; RIH domain
      pfam02026
      Location:849 → 937
      RyR; RyR domain
      pfam02815
      Location:216 → 397
      MIR; MIR domain
      pfam06459
      Location:4227 → 4497
      RR_TM4-6; Ryanodine Receptor TM 4-6
      pfam08454
      Location:3724 → 3837
      RIH_assoc; RyR and IP3R Homology associated
      pfam13499
      Location:3921 → 3976
      EF-hand_7; EF-hand domain pair
      cl19745
      Location:12 → 207
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    12. XM_017022476.2 → XP_016877965.1  ryanodine receptor 3 isoform X13

      UniProtKB/TrEMBL
      A0A0X1KG73

    13. XM_047432933.1 → XP_047288889.1  ryanodine receptor 3 isoform X14

      UniProtKB/TrEMBL
      A0A0X1KG73

    14. XM_017022477.2 → XP_016877966.1  ryanodine receptor 3 isoform X15

    15. XM_017022474.2 → XP_016877963.1  ryanodine receptor 3 isoform X9

      UniProtKB/TrEMBL
      A0A0X1KG73

    16. XM_017022470.3 → XP_016877959.1  ryanodine receptor 3 isoform X3

      UniProtKB/TrEMBL
      A0A0X1KG73

    RNA

    1. XR_001751370.2 RNA Sequence

    2. XR_001751371.3 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060939.1 Alternate T2T-CHM13v2.0

      Range
      31107439..31663747
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054378594.1 → XP_054234569.1  ryanodine receptor 3 isoform X10

      UniProtKB/TrEMBL
      A0A0X1KG73

    2. XM_054378586.1 → XP_054234561.1  ryanodine receptor 3 isoform X1

      UniProtKB/TrEMBL
      A0A0X1KG73

    3. XM_054378595.1 → XP_054234570.1  ryanodine receptor 3 isoform X11

      UniProtKB/TrEMBL
      A0A0X1KG73

    4. XM_054378592.1 → XP_054234567.1  ryanodine receptor 3 isoform X7

      UniProtKB/TrEMBL
      A0A0X1KG73

    5. XM_054378596.1 → XP_054234571.1  ryanodine receptor 3 isoform X12

      UniProtKB/TrEMBL
      A0A0X1KG73

    6. XM_054378587.1 → XP_054234562.1  ryanodine receptor 3 isoform X2

      UniProtKB/TrEMBL
      A0A0X1KG73

    7. XM_054378590.1 → XP_054234565.1  ryanodine receptor 3 isoform X5

      UniProtKB/TrEMBL
      A0A0X1KG73

    8. XM_054378588.1 → XP_054234563.1  ryanodine receptor 3 isoform X4

      UniProtKB/TrEMBL
      A0A0X1KG73

    9. XM_054378591.1 → XP_054234566.1  ryanodine receptor 3 isoform X6

      UniProtKB/TrEMBL
      A0A0X1KG73

    10. XM_054378600.1 → XP_054234575.1  ryanodine receptor 3 isoform X16

      UniProtKB/TrEMBL
      A0A0X1KG73

    11. XM_054378597.1 → XP_054234572.1  ryanodine receptor 3 isoform X13

      UniProtKB/TrEMBL
      A0A0X1KG73

    12. XM_054378598.1 → XP_054234573.1  ryanodine receptor 3 isoform X14

      UniProtKB/TrEMBL
      A0A0X1KG73

    13. XM_054378599.1 → XP_054234574.1  ryanodine receptor 3 isoform X15

    14. XM_054378593.1 → XP_054234568.1  ryanodine receptor 3 isoform X9

      UniProtKB/TrEMBL
      A0A0X1KG73

    15. XM_054378589.1 → XP_054234564.1  ryanodine receptor 3 isoform X3

      UniProtKB/TrEMBL
      A0A0X1KG73

    RNA

    1. XR_008489001.1 RNA Sequence

    2. XR_008489002.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q15413.3 GenPept UniProtKB/Swiss-Prot:Q15413

    Gene LinkOut

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