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    C10orf143 chromosome 10 open reading frame 143 [ Homo sapiens (human) ]

    Gene ID: 387723, updated on 10-Dec-2024

    Summary

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    Official Symbol
    C10orf143provided by HGNC
    Official Full Name
    chromosome 10 open reading frame 143provided by HGNC
    Primary source
    HGNC:HGNC:48677
    See related
    Ensembl:ENSG00000237489 AllianceGenome:HGNC:48677
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    LINC00959
    Expression
    Ubiquitous expression in thyroid (RPKM 1.2), prostate (RPKM 1.0) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See C10orf143 in Genome Data Viewer
    Location:
    10q26.3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (130035125..130110830, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (130961816..131039821, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (131862160..131909094, complement)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene microRNA 4297 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131664970-131665634 Neighboring gene EBF transcription factor 3 Neighboring gene EBF3 antisense RNA 1 Neighboring gene VISTA enhancer hs232 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131692870-131693478 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:131694193-131695097 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:131695098-131696001 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131725181-131725712 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131747356-131748190 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:131756502-131757174 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131758519-131759190 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:131762665-131763636 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131764672-131765292 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:131766535-131767154 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr10:131769017-131769636 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:131770277-131771162 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:131771163-131772046 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131811814-131812654 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131842637-131843136 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131847250-131848134 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131903776-131904291 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4205 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4206 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4207 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2941 Neighboring gene uncharacterized LOC102724883 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4208 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4209 Neighboring gene uncharacterized LOC124902560 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131919446-131919946 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131919947-131920447 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_11122 Neighboring gene uncharacterized LOC105378561 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_11124 Neighboring gene CTAGE family member 7, pseudogene Neighboring gene peptidylprolyl isomerase A pseudogene 32

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    uncharacterized protein C10orf143
    Names
    long intergenic non-protein coding RNA 959

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355042.2 → NP_001341971.1  uncharacterized protein C10orf143

      Status: VALIDATED

      Source sequence(s)
      AL139123
      Consensus CDS
      CCDS86157.1
      UniProtKB/Swiss-Prot
      A0A1B0GUT2
      Related
      ENSP00000490233.1, ENST00000637128.2

    RNA

    1. NR_034125.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AK094118, AL139123, AW135007, EU250747
      Related
      ENST00000647406.1

    2. NR_149170.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL139123

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      130035125..130110830 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024448009.2 → XP_024303777.1  uncharacterized protein C10orf143 isoform X3

      UniProtKB/TrEMBL
      A0A2R8YF93
      Related
      ENSP00000496273.1, ENST00000643056.1

    2. XM_024448007.2 → XP_024303775.1  uncharacterized protein C10orf143 isoform X1

    3. XM_024448008.2 → XP_024303776.1  uncharacterized protein C10orf143 isoform X2

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      130961816..131039821 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054365906.1 → XP_054221881.1  uncharacterized protein C10orf143 isoform X3

      UniProtKB/TrEMBL
      A0A2R8YF93

    2. XM_054365904.1 → XP_054221879.1  uncharacterized protein C10orf143 isoform X1

    3. XM_054365905.1 → XP_054221880.1  uncharacterized protein C10orf143 isoform X2

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A1B0GUT2.1 GenPept UniProtKB/Swiss-Prot:A0A1B0GUT2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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    Research Materials