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    LINC01159 long intergenic non-protein coding RNA 1159 [ Homo sapiens (human) ]

    Gene ID: 102682016, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC01159provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 1159provided by HGNC
    Primary source
    HGNC:HGNC:49514
    See related
    Ensembl:ENSG00000229743 MIM:618208; AllianceGenome:HGNC:49514
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    linc-Brn1b
    Summary
    Predicted to act upstream of or within cerebellar cortex structural organization; homeostasis of number of cells within a tissue; and regulation of gene expression. Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward kidney (RPKM 2.1) See more
    Orthologs
    mouse all
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    Genomic context

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    See LINC01159 in Genome Data Viewer
    Location:
    2q12.1
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (104865497..104872595, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (105326681..105333779, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (105481955..105489053, complement)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene POU3F3 adjacent non-coding transcript 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:105460844-105461368 Neighboring gene VISTA enhancer hs1553 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11835 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr2:105470177-105470766 Neighboring gene uncharacterized LOC124908045 Neighboring gene Sharpr-MPRA regulatory region 193 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr2:105488734-105489459 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11836 Neighboring gene POU class 3 homeobox 3 Neighboring gene VISTA enhancer hs990 Neighboring gene MRPS9 antisense RNA 2 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:105585853-105587052 Neighboring gene Sharpr-MPRA regulatory region 1600 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:105621477-105622097 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16309 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16310 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16311 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:105654567-105655509 Neighboring gene mitochondrial ribosomal protein S9 Neighboring gene VISTA enhancer hs868 Neighboring gene uncharacterized LOC105373527 Neighboring gene MRPS9 antisense RNA 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Multiple knockout mouse models reveal lincRNAs are required for life and brain development. Sauvageau M, et al. Elife, 2013 Dec 31. PMID 24381249, Free PMC Article
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Homology

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_110373.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      AC018730
      Related
      ENST00000433433.1

    2. NR_110374.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate 3' exon, resulting in a shorter transcript, compared to variant 1.
      Source sequence(s)
      AC018730

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      104865497..104872595 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      105326681..105333779 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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