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    EIF4E2 eukaryotic translation initiation factor 4E family member 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 519920, updated on 27-Dec-2024

    Summary

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    Official Symbol
    EIF4E2provided by VGNC
    Official Full Name
    eukaryotic translation initiation factor 4E family member 2provided by VGNC
    Primary source
    VGNC:VGNC:28410
    See related
    BGD:BT27983; Ensembl:ENSBTAG00000010598
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See EIF4E2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (120187397..120218347)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene cholinergic receptor nicotinic delta subunit Neighboring gene uncharacterized LOC112443174 Neighboring gene cholinergic receptor nicotinic gamma subunit Neighboring gene uncharacterized LOC101906781 Neighboring gene inward rectifier potassium channel 13-like Neighboring gene polyhomeotic homolog 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC152103

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA 7-methylguanosine cap binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in translational initiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of eukaryotic translation initiation factor 4F complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    eukaryotic translation initiation factor 4E type 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075795.2 → NP_001069263.1  eukaryotic translation initiation factor 4E type 2 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the shorter isoform (1).
      Source sequence(s)
      BC122831, NKLS02000002
      UniProtKB/TrEMBL
      Q0II31
      Related
      ENSBTAP00000067250.1, ENSBTAT00000070208.1
      Conserved Domains (1) summary
      pfam01652
      Location:55 → 214
      IF4E; Eukaryotic initiation factor 4E

    2. NM_001206416.1 → NP_001193345.1  eukaryotic translation initiation factor 4E type 2 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice pattern in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (2) has a longer and distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      EH132414, EV682356, EV746051
      Related
      ENSBTAP00000049866.3, ENSBTAT00000055491.3
      Conserved Domains (1) summary
      pfam01652
      Location:55 → 214
      IF4E; Eukaryotic initiation factor 4E

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      120187397..120218347
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010802425.2 → XP_010800727.1  eukaryotic translation initiation factor 4E type 2 isoform X4

      UniProtKB/TrEMBL
      A0AAA9TS51
      Related
      ENSBTAP00000101207.1, ENSBTAT00000116679.1
      Conserved Domains (1) summary
      pfam01652
      Location:55 → 214
      IF4E; Eukaryotic initiation factor 4E

    2. XM_059874538.1 → XP_059730521.1  eukaryotic translation initiation factor 4E type 2 isoform X3

    3. XM_059874537.1 → XP_059730520.1  eukaryotic translation initiation factor 4E type 2 isoform X2

    4. XM_059874534.1 → XP_059730517.1  eukaryotic translation initiation factor 4E type 2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LSC2
      Related
      ENSBTAP00000059919.2, ENSBTAT00000084173.2
    Nucleotide Protein Strain
    Heading Accession and Version

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