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    POLD3 DNA polymerase delta 3, accessory subunit [ Bos taurus (domestic cattle) ]

    Gene ID: 537616, updated on 29-Jan-2025

    Summary

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    Official Symbol
    POLD3provided by VGNC
    Official Full Name
    DNA polymerase delta 3, accessory subunitprovided by VGNC
    Primary source
    VGNC:VGNC:33115
    See related
    Ensembl:ENSBTAG00000016869
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    P68
    Orthologs
    human mouse all
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    Genomic context

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    See POLD3 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (53909173..53953518)

    Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132342343 Neighboring gene potassium voltage-gated channel subfamily E regulatory subunit 3 Neighboring gene lipoyl(octanoyl) transferase 2 Neighboring gene chordin like 2 Neighboring gene U6 spliceosomal RNA Neighboring gene ring finger protein 169

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Identification of a fourth subunit of mammalian DNA polymerase delta. Liu L, et al. J Biol Chem, 2000 Jun 23. PMID 10751307
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-directed DNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA strand elongation involved in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA synthesis involved in UV-damage excision repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nucleotide-excision repair, DNA gap filling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of delta DNA polymerase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA polymerase delta subunit 3
    Names
    DNA polymerase delta subunit p66
    DNA-directed DNA polymerase delta 3
    polymerase (DNA-directed), delta 3, accessory subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001167904.3 → NP_001161376.1  DNA polymerase delta subunit 3

      See identical proteins and their annotated locations for NP_001161376.1

      Status: VALIDATED

      Source sequence(s)
      BC151727, EH162138, NKLS02000015
      UniProtKB/Swiss-Prot
      P84798
      Related
      ENSBTAP00070047046.1, ENSBTAT00070077210.1
      Conserved Domains (1) summary
      pfam09507
      Location:19 → 464
      CDC27; DNA polymerase subunit Cdc27

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      53909173..53953518
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010812697.4 → XP_010810999.1  DNA polymerase delta subunit 3 isoform X1

      UniProtKB/TrEMBL
      A0AAF6ZFA9, G1K1U4
      Conserved Domains (1) summary
      pfam09507
      Location:55 → 498
      CDC27; DNA polymerase subunit Cdc27

    2. XM_010812698.3 → XP_010811000.1  DNA polymerase delta subunit 3 isoform X2

      UniProtKB/TrEMBL
      A0AAF6ZFA9
      Related
      ENSBTAP00070047031.1, ENSBTAT00070077189.1
      Conserved Domains (1) summary
      pfam09507
      Location:52 → 495
      CDC27; DNA polymerase subunit Cdc27

    3. XM_010812699.4 → XP_010811001.1  DNA polymerase delta subunit 3 isoform X4

      Conserved Domains (2) summary
      pfam09507
      Location:55 → 378
      CDC27; DNA polymerase subunit Cdc27
      cl00641
      Location:311 → 362
      Cas4_I-A_I-B_I-C_I-D_II-B; CRISPR/Cas system-associated protein Cas4

    4. XM_059874889.1 → XP_059730872.1  DNA polymerase delta subunit 3 isoform X3

      UniProtKB/TrEMBL
      A0AAF6ZFA9
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P84798.2 GenPept UniProtKB/Swiss-Prot:P84798

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