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    PPP1R42 protein phosphatase 1 regulatory subunit 42 [ Bos taurus (domestic cattle) ]

    Gene ID: 506058, updated on 27-Dec-2024

    Summary

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    Official Symbol
    PPP1R42provided by VGNC
    Official Full Name
    protein phosphatase 1 regulatory subunit 42provided by VGNC
    Primary source
    VGNC:VGNC:53877
    See related
    BGD:BT18466; Ensembl:ENSBTAG00000011205
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    LRRC67
    Orthologs
    human mouse all
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    Genomic context

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    See PPP1R42 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 14 NC_037341.1 (31135383..31181805, complement)

    Chromosome 14 - NC_037341.1Genomic Context describing neighboring genes Neighboring gene minichromosome maintenance domain containing 2 Neighboring gene nuclear ubiquitous casein and cyclin-dependent kinase substrate 1-like Neighboring gene uncharacterized LOC100847363 Neighboring gene small nucleolar RNA SNORD87 Neighboring gene transcription factor 24 Neighboring gene uncharacterized LOC112449622 Neighboring gene COP9 signalosome subunit 5 Neighboring gene centrosome and spindle pole associated protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037341.1 Chromosome 14 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC127941

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein phosphatase 1 regulatory subunit 42
    Names
    leucine rich repeat containing 67

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075238.3 → NP_001068706.2  protein phosphatase 1 regulatory subunit 42

      Status: VALIDATED

      Source sequence(s)
      DT855618, DT860989, NKLS02000014
      UniProtKB/TrEMBL
      Q3SZY4
      Related
      ENSBTAP00000102510.1, ENSBTAT00000133687.1
      Conserved Domains (2) summary
      sd00033
      Location:30 → 51
      LRR_RI; leucine-rich repeat [structural motif]
      pfam14580
      Location:144 → 237
      LRR_9; Leucine-rich repeat

    RNA

    1. NR_153377.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      DT860989, EH202590, NKLS02000014
      Related
      ENSBTAT00000014881.7

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037341.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      31135383..31181805 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059893151.1 → XP_059749134.1  protein phosphatase 1 regulatory subunit 42 isoform X2

      UniProtKB/TrEMBL
      Q3SZY4

    2. XM_025001455.2 → XP_024857223.1  protein phosphatase 1 regulatory subunit 42 isoform X7

      UniProtKB/TrEMBL
      A0AAA9TVJ5
      Related
      ENSBTAP00000101168.1, ENSBTAT00000117562.1
      Conserved Domains (3) summary
      sd00031
      Location:108 → 137
      LRR_1; leucine-rich repeat [structural motif]
      pfam13971
      Location:43 → 196
      Mei4; Meiosis-specific protein Mei4
      pfam14580
      Location:134 → 227
      LRR_9; Leucine-rich repeat

    3. XM_005215462.5 → XP_005215519.1  protein phosphatase 1 regulatory subunit 42 isoform X5

      Conserved Domains (3) summary
      pfam14580
      Location:109 → 227
      LRR_9; Leucine-rich repeat
      sd00031
      Location:108 → 137
      LRR_1; leucine-rich repeat [structural motif]
      pfam12799
      Location:136 → 177
      LRR_4; Leucine Rich repeats (2 copies)

    4. XM_005215461.5 → XP_005215518.1  protein phosphatase 1 regulatory subunit 42 isoform X4

      Conserved Domains (3) summary
      pfam14580
      Location:109 → 232
      LRR_9; Leucine-rich repeat
      sd00031
      Location:108 → 142
      LRR_1; leucine-rich repeat [structural motif]
      pfam12799
      Location:141 → 182
      LRR_4; Leucine Rich repeats (2 copies)

    5. XM_059893152.1 → XP_059749135.1  protein phosphatase 1 regulatory subunit 42 isoform X3

      UniProtKB/TrEMBL
      A0AAA9SF42, Q3SZY4
      Related
      ENSBTAP00000081059.1, ENSBTAT00000130457.1

    6. XM_005215463.5 → XP_005215520.1  protein phosphatase 1 regulatory subunit 42 isoform X6

      UniProtKB/TrEMBL
      A0AAF6DM87, Q3SZY4
      Related
      ENSBTAP00000044218.3, ENSBTAT00000046974.4
      Conserved Domains (4) summary
      pfam14580
      Location:149 → 242
      LRR_9; Leucine-rich repeat
      sd00033
      Location:30 → 51
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:72 → 114
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:50 → 106
      LRR_8; Leucine rich repeat

    7. XM_005215459.5 → XP_005215516.1  protein phosphatase 1 regulatory subunit 42 isoform X1

      UniProtKB/TrEMBL
      Q3SZY4
      Conserved Domains (4) summary
      pfam14580
      Location:144 → 237
      LRR_9; Leucine-rich repeat
      sd00033
      Location:30 → 51
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:72 → 114
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:50 → 106
      LRR_8; Leucine rich repeat
    Nucleotide Protein Strain
    Heading Accession and Version

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