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    IRF5 interferon regulatory factor 5 [ Bos taurus (domestic cattle) ]

    Gene ID: 615340, updated on 27-Dec-2024

    Summary

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    Official Symbol
    IRF5provided by VGNC
    Official Full Name
    interferon regulatory factor 5provided by VGNC
    Primary source
    VGNC:VGNC:30276
    See related
    BGD:BT24505; Ensembl:ENSBTAG00000004989
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See IRF5 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (92892434..92905306)

    Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene collagen alpha-1(I) chain Neighboring gene 2-iminobutanoate/2-iminopropanoate deaminase-like Neighboring gene kielin cysteine rich BMP regulator Neighboring gene transportin 3 Neighboring gene uncharacterized LOC132345128 Neighboring gene microRNA mir-1843

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in immune system process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interferon regulatory factor 5
    Names
    IRF-5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035465.1 → NP_001030542.1  interferon regulatory factor 5

      See identical proteins and their annotated locations for NP_001030542.1

      Status: PROVISIONAL

      Source sequence(s)
      BT021607
      UniProtKB/Swiss-Prot
      Q58DJ0
      UniProtKB/TrEMBL
      A0A3Q1MGV4
      Related
      ENSBTAP00000006567.5, ENSBTAT00000006567.6
      Conserved Domains (2) summary
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:249 → 432
      IRF-3; Interferon-regulatory factor 3

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      92892434..92905306
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059885742.1 → XP_059741725.1  interferon regulatory factor 5 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MGV4, B0JYR2

    2. XM_059885744.1 → XP_059741727.1  interferon regulatory factor 5 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MGV4, B0JYR2

    3. XM_059885743.1 → XP_059741726.1  interferon regulatory factor 5 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MGV4, B0JYR2

    4. XM_059885745.1 → XP_059741728.1  interferon regulatory factor 5 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MGV4, B0JYR2

    5. XM_005205732.5 → XP_005205789.1  interferon regulatory factor 5 isoform X2

      See identical proteins and their annotated locations for XP_005205789.1

      UniProtKB/TrEMBL
      A0A3Q1MGV4, B0JYR2
      Related
      ENSBTAP00000070238.2, ENSBTAT00000072681.2
      Conserved Domains (2) summary
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:249 → 432
      IRF-3; Interferon-regulatory factor 3

    6. XM_059885746.1 → XP_059741729.1  interferon regulatory factor 5 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MGV4, B0JYR2

    7. XM_059885741.1 → XP_059741724.1  interferon regulatory factor 5 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MGV4
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q58DJ0.1 GenPept UniProtKB/Swiss-Prot:Q58DJ0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.