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    ERCC3 ERCC excision repair 3, TFIIH core complex helicase subunit [ Bos taurus (domestic cattle) ]

    Gene ID: 507984, updated on 29-Jan-2025

    Summary

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    Official Symbol
    ERCC3provided by VGNC
    Official Full Name
    ERCC excision repair 3, TFIIH core complex helicase subunitprovided by VGNC
    Primary source
    VGNC:VGNC:28570
    See related
    BGD:BT27157; Ensembl:ENSBTAG00000020777
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ERCC3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (5248743..5279068)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene protein C, inactivator of coagulation factors Va and VIIIa Neighboring gene mitogen-activated protein kinase kinase kinase 2 Neighboring gene microRNA mir-2285aa Neighboring gene cytochrome P450 family 27 subfamily C member 1 Neighboring gene large ribosomal subunit protein eL6-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC137777

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3'-5' DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in embryonic organ development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in hair cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nucleotide-excision repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transcription initiation at RNA polymerase II promoter IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of nucleotide-excision repair factor 3 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of transcription factor TFIIH holo complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of transcription preinitiation complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    general transcription and DNA repair factor IIH helicase/translocase subunit XPB
    Names
    DNA 3'-5' helicase/translocase XPB
    DNA excision repair protein ERCC-3
    TFIIH basal transcription factor complex helicase XPB subunit
    TFIIH subunit XPB
    excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)
    general transcription and DNA repair factor IIH helicase subunit XPB
    NP_001039453.1
    XP_015329897.1
    XP_024855871.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045988.1 → NP_001039453.1  general transcription and DNA repair factor IIH helicase/translocase subunit XPB

      See identical proteins and their annotated locations for NP_001039453.1

      Status: PROVISIONAL

      Source sequence(s)
      BC114729
      UniProtKB/Swiss-Prot
      Q1RMT1
      UniProtKB/TrEMBL
      A0A3Q1MFX7
      Related
      ENSBTAP00070002324.1, ENSBTAT00070004154.1
      Conserved Domains (1) summary
      TIGR00603
      Location:60 → 779
      rad25; DNA repair helicase rad25

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      5248743..5279068
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025000103.2 → XP_024855871.1  general transcription and DNA repair factor IIH helicase/translocase subunit XPB isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MFX7
      Conserved Domains (1) summary
      TIGR00603
      Location:1 → 715
      rad25; DNA repair helicase rad25

    2. XM_015474411.3 → XP_015329897.1  general transcription and DNA repair factor IIH helicase/translocase subunit XPB isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MFX7
      Conserved Domains (1) summary
      TIGR00603
      Location:1 → 715
      rad25; DNA repair helicase rad25
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1RMT1.1 GenPept UniProtKB/Swiss-Prot:Q1RMT1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.