U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    LIMS2 LIM zinc finger domain containing 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 515401, updated on 29-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    LIMS2provided by VGNC
    Official Full Name
    LIM zinc finger domain containing 2provided by VGNC
    Primary source
    VGNC:VGNC:30891
    See related
    BGD:BT27341; Ensembl:ENSBTAG00000006262
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    LIMS1
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See LIMS2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (4842279..4886378)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene WD repeat domain 33 Neighboring gene SFT2 domain containing 3 Neighboring gene G protein-coupled receptor 17 Neighboring gene myosin VIIB Neighboring gene interacts with SUPT6H, CTD assembly factor 1 Neighboring gene transfer RNA glutamic acid (anticodon UUC)

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-cell junction organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of substrate adhesion-dependent cell spreading IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell-cell junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    LIM and senescent cell antigen-like-containing domain protein 2
    Names
    LIM and senescent cell antigen-like domains 1
    LIM and senescent cell antigen-like domains 2
    PINCH-2
    particularly interesting new Cys-His protein 2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001130751.1 → NP_001124223.1  LIM and senescent cell antigen-like-containing domain protein 2

      Status: PROVISIONAL

      Source sequence(s)
      BC105544
      UniProtKB/Swiss-Prot
      Q2KJ33
      UniProtKB/TrEMBL
      A0AAF6YPK5
      Related
      ENSBTAP00070002208.1, ENSBTAT00070003968.1
      Conserved Domains (5) summary
      cd09331
      Location:15 → 73
      LIM1_PINCH; The first LIM domain of protein PINCH
      cd09332
      Location:76 → 127
      LIM2_PINCH; The second LIM domain of protein PINCH
      cd09333
      Location:140 → 190
      LIM3_PINCH; The third LIM domain of protein PINCH
      cd09334
      Location:196 → 249
      LIM4_PINCH; The fourth LIM domain of protein PINCH
      cd09335
      Location:257 → 310
      LIM5_PINCH; The fifth LIM domain of protein PINCH

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      4842279..4886378
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005202198.4 → XP_005202255.1  LIM and senescent cell antigen-like-containing domain protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LTN6, A0AAF6YPK5
      Conserved Domains (5) summary
      cd09331
      Location:10 → 68
      LIM1_PINCH; The first LIM domain of protein PINCH
      cd09332
      Location:71 → 122
      LIM2_PINCH; The second LIM domain of protein PINCH
      cd09333
      Location:135 → 185
      LIM3_PINCH; The third LIM domain of protein PINCH
      cd09334
      Location:191 → 244
      LIM4_PINCH; The fourth LIM domain of protein PINCH
      cd09335
      Location:252 → 305
      LIM5_PINCH; The fifth LIM domain of protein PINCH

    2. XM_005202197.4 → XP_005202254.1  LIM and senescent cell antigen-like-containing domain protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1NLE9, A0AAF6YPK5
      Related
      ENSBTAP00070002205.1, ENSBTAT00070003964.1
      Conserved Domains (5) summary
      cd09331
      Location:40 → 98
      LIM1_PINCH; The first LIM domain of protein PINCH
      cd09332
      Location:101 → 152
      LIM2_PINCH; The second LIM domain of protein PINCH
      cd09333
      Location:165 → 215
      LIM3_PINCH; The third LIM domain of protein PINCH
      cd09334
      Location:221 → 274
      LIM4_PINCH; The fourth LIM domain of protein PINCH
      cd09335
      Location:282 → 335
      LIM5_PINCH; The fifth LIM domain of protein PINCH

    3. XM_059874353.1 → XP_059730336.1  LIM and senescent cell antigen-like-containing domain protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LTN6, A0AAF6YPK5

    4. XM_059874345.1 → XP_059730328.1  LIM and senescent cell antigen-like-containing domain protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LTN6, A0AAF6YPK5

    5. XM_059874362.1 → XP_059730345.1  LIM and senescent cell antigen-like-containing domain protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LTN6, A0AAF6YPK5
      Related
      ENSBTAP00070002212.1, ENSBTAT00070003974.1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2KJ33.2 GenPept UniProtKB/Swiss-Prot:Q2KJ33

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.