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    TRIM56 tripartite motif containing 56 [ Bos taurus (domestic cattle) ]

    Gene ID: 514896, updated on 1-Jan-2025

    Summary

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    Official Symbol
    TRIM56provided by VGNC
    Official Full Name
    tripartite motif containing 56provided by VGNC
    Primary source
    VGNC:VGNC:36342
    See related
    BGD:BT21076; Ensembl:ENSBTAG00000012038
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See TRIM56 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (35626743..35635577, complement)

    Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101902751 Neighboring gene serpin family E member 1 Neighboring gene mucin-12 Neighboring gene mucin-3A Neighboring gene mucin-3A-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein monoubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase TRIM56
    Names
    RING-type E3 ubiquitin transferase TRIM56
    tripartite motif-containing protein 56
    NP_001193503.1
    XP_024840599.1
    XP_024840600.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206574.1 → NP_001193503.1  E3 ubiquitin-protein ligase TRIM56

      Status: VALIDATED

      Source sequence(s)
      AAFC03118057
      UniProtKB/Swiss-Prot
      E1BD59
      UniProtKB/TrEMBL
      A0AAA9SZH9
      Conserved Domains (6) summary
      cd00021
      Location:169 → 205
      BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
      cd05819
      Location:552 → 626
      NHL; NHL repeat [structural motif]
      sd00039
      Location:579 → 627
      7WD40; WD40 repeat [structural motif]
      cl18310
      Location:520 → 748
      NHL; NHL repeat unit of beta-propeller proteins
      cd16584
      Location:19 → 60
      RING-HC_TRIM56_C-V; RING finger, HC subclass, found in tripartite motif-containing protein 56 (TRIM56) and similar proteins
      cl26527
      Location:207 → 295
      ClpB_D2-small; C-terminal, D2-small domain, of ClpB protein

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      35626743..35635577 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024984832.2 → XP_024840600.1  E3 ubiquitin-protein ligase TRIM56 isoform X1

      UniProtKB/Swiss-Prot
      E1BD59
      UniProtKB/TrEMBL
      A0AAA9SZH9
      Related
      ENSBTAP00000087794.1, ENSBTAT00000096773.1
      Conserved Domains (6) summary
      cd00021
      Location:169 → 205
      BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
      cd05819
      Location:552 → 626
      NHL; NHL repeat [structural motif]
      sd00039
      Location:579 → 627
      7WD40; WD40 repeat [structural motif]
      cl18310
      Location:520 → 748
      NHL; NHL repeat unit of beta-propeller proteins
      cd16584
      Location:19 → 60
      RING-HC_TRIM56_C-V; RING finger, HC subclass, found in tripartite motif-containing protein 56 (TRIM56) and similar proteins
      cl26527
      Location:207 → 295
      ClpB_D2-small; C-terminal, D2-small domain, of ClpB protein

    2. XM_024984831.2 → XP_024840599.1  E3 ubiquitin-protein ligase TRIM56 isoform X1

      UniProtKB/Swiss-Prot
      E1BD59
      UniProtKB/TrEMBL
      A0AAA9SZH9
      Related
      ENSBTAP00000103554.1, ENSBTAT00000109349.1
      Conserved Domains (6) summary
      cd00021
      Location:169 → 205
      BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
      cd05819
      Location:552 → 626
      NHL; NHL repeat [structural motif]
      sd00039
      Location:579 → 627
      7WD40; WD40 repeat [structural motif]
      cl18310
      Location:520 → 748
      NHL; NHL repeat unit of beta-propeller proteins
      cd16584
      Location:19 → 60
      RING-HC_TRIM56_C-V; RING finger, HC subclass, found in tripartite motif-containing protein 56 (TRIM56) and similar proteins
      cl26527
      Location:207 → 295
      ClpB_D2-small; C-terminal, D2-small domain, of ClpB protein
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E1BD59.1 GenPept UniProtKB/Swiss-Prot:E1BD59

    Gene LinkOut

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