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    MIOS meiosis regulator for oocyte development [ Bos taurus (domestic cattle) ]

    Gene ID: 512321, updated on 27-Dec-2024

    Summary

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    Official Symbol
    MIOSprovided by VGNC
    Official Full Name
    meiosis regulator for oocyte developmentprovided by VGNC
    Primary source
    VGNC:VGNC:31481
    See related
    BGD:BT14805; Ensembl:ENSBTAG00000013781
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
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    Genomic context

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    See MIOS in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (15634964..15672063)

    Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 Neighboring gene collagen type XXVIII alpha 1 chain Neighboring gene transfer RNA serine (anticodon GCU) Neighboring gene pancreatic progenitor cell differentiation and proliferation factor-like Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene UBAP1-MVB12-associated (UMA) domain containing 1 Neighboring gene replication protein A3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to amino acid starvation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of TORC1 signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GATOR2 complex protein MIOS

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192318.1 → NP_001179247.1  GATOR2 complex protein MIOS

      See identical proteins and their annotated locations for NP_001179247.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000004
      UniProtKB/TrEMBL
      E1B899
      Related
      ENSBTAP00000018305.5, ENSBTAT00000018305.6
      Conserved Domains (3) summary
      COG2319
      Location:89 → 368
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:64 → 105
      7WD40; WD40 repeat [structural motif]
      cd16691
      Location:782 → 858
      mRING-H2-C3H3C2_Mio; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein mio and simialr proteins

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      15634964..15672063
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005205180.5 → XP_005205237.1  GATOR2 complex protein MIOS isoform X1

      See identical proteins and their annotated locations for XP_005205237.1

      UniProtKB/TrEMBL
      E1B899
      Conserved Domains (3) summary
      COG2319
      Location:89 → 368
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:64 → 105
      7WD40; WD40 repeat [structural motif]
      cd16691
      Location:782 → 858
      mRING-H2-C3H3C2_Mio; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein mio and simialr proteins

    2. XM_024990624.2 → XP_024846392.1  GATOR2 complex protein MIOS isoform X1

      UniProtKB/TrEMBL
      E1B899
      Conserved Domains (3) summary
      COG2319
      Location:89 → 368
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:64 → 105
      7WD40; WD40 repeat [structural motif]
      cd16691
      Location:782 → 858
      mRING-H2-C3H3C2_Mio; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein mio and simialr proteins

    3. XM_024990622.2 → XP_024846390.1  GATOR2 complex protein MIOS isoform X1

      UniProtKB/TrEMBL
      E1B899
      Conserved Domains (3) summary
      COG2319
      Location:89 → 368
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:64 → 105
      7WD40; WD40 repeat [structural motif]
      cd16691
      Location:782 → 858
      mRING-H2-C3H3C2_Mio; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein mio and simialr proteins

    4. XM_005205181.3 → XP_005205238.1  GATOR2 complex protein MIOS isoform X1

      See identical proteins and their annotated locations for XP_005205238.1

      UniProtKB/TrEMBL
      E1B899
      Conserved Domains (3) summary
      COG2319
      Location:89 → 368
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:64 → 105
      7WD40; WD40 repeat [structural motif]
      cd16691
      Location:782 → 858
      mRING-H2-C3H3C2_Mio; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein mio and simialr proteins

    5. XM_024990623.2 → XP_024846391.1  GATOR2 complex protein MIOS isoform X1

      UniProtKB/TrEMBL
      E1B899
      Conserved Domains (3) summary
      COG2319
      Location:89 → 368
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:64 → 105
      7WD40; WD40 repeat [structural motif]
      cd16691
      Location:782 → 858
      mRING-H2-C3H3C2_Mio; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein mio and simialr proteins

    6. XM_005205179.3 → XP_005205236.1  GATOR2 complex protein MIOS isoform X1

      See identical proteins and their annotated locations for XP_005205236.1

      UniProtKB/TrEMBL
      E1B899
      Conserved Domains (3) summary
      COG2319
      Location:89 → 368
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:64 → 105
      7WD40; WD40 repeat [structural motif]
      cd16691
      Location:782 → 858
      mRING-H2-C3H3C2_Mio; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein mio and simialr proteins

    7. XM_059885532.1 → XP_059741515.1  GATOR2 complex protein MIOS isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version

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