ARPC1B actin related protein 2/3 complex subunit 1B [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: ARPC1Bprovided by VGNC
Official Full Name: actin related protein 2/3 complex subunit 1Bprovided by VGNC
Primary source: VGNC:VGNC:26164
See related: BGD:BT13024; Ensembl:ENSBTAG00000046248
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 25

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	25	NC_037352.1 (37005090..37017683, complement)

Chromosome 25 - NC_037352.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The GMF-Arp2 interface reveals how the ADF-H actin-binding domain in GMF is exploited to specifically recognize Arp2/3 complex and not actin.
Title: Structural basis for regulation of Arp2/3 complex by GMF.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables actin filament binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Arp2/3 complex-mediated actin nucleation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of Arp2/3 protein complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in actin cytoskeleton	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: actin-related protein 2/3 complex subunit 1B

Names: actin related protein 2/3 complex, subunit 1B, 41kDa; arp2/3 complex 41 kDa subunit; p41-ARC

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001014844.3 → NP_001014844.1 actin-related protein 2/3 complex subunit 1B

See identical proteins and their annotated locations for NP_001014844.1

Status: PROVISIONAL

Source sequence(s)

BC102942

UniProtKB/Swiss-Prot

Q0V8Q8, Q58CQ2, Q58DS1

UniProtKB/TrEMBL

Q0V8E5, Q1JPK9

Related

ENSBTAP00000091612.1, ENSBTAT00000116825.1

Conserved Domains (2) summary

sd00039
Location:11 → 50

7WD40; WD40 repeat [structural motif]

cl29593
Location:45 → 264

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...