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    ITGB1BP2 integrin subunit beta 1 binding protein 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 539945, updated on 30-Jan-2025

    Summary

    Official Symbol
    ITGB1BP2provided by VGNC
    Official Full Name
    integrin subunit beta 1 binding protein 2provided by VGNC
    Primary source
    VGNC:VGNC:30326
    See related
    BGD:BT12290; EnsemblRapid:ENSBTAG00070034499
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
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    Genomic context

    See ITGB1BP2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (79330102..79367534, complement)

    Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L36a-like pseudogene Neighboring gene U6 spliceosomal RNA Neighboring gene non-POU domain containing octamer binding Neighboring gene zinc finger MYM-type containing 3

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

    Expression

    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    General protein information

    Preferred Names
    integrin beta-1-binding protein 2
    Names
    integrin beta 1 binding protein (melusin) 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205732.1NP_001192661.1  integrin beta-1-binding protein 2

      See identical proteins and their annotated locations for NP_001192661.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000030
      UniProtKB/TrEMBL
      A0A3Q1M676, E1BHP7
      Related
      ENSBTAP00070047336.1, ENSBTAT00070077576.1
      Conserved Domains (2) summary
      cd06488
      Location:219305
      p23_melusin_like; p23_like domain similar to the C-terminal (tail) domain of vertebrate Melusin and related proteins. Melusin's tail domain interacts with the cytoplasmic domain of beta1-A and beta1-D isoforms of beta1 integrin, it does not bind other integrin beta ...
      pfam04968
      Location:364
      CHORD; CHORD

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      79330102..79367534 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059883507.1XP_059739490.1  integrin beta-1-binding protein 2 isoform X1

    2. XM_010821852.4XP_010820154.1  integrin beta-1-binding protein 2 isoform X2

      Conserved Domains (2) summary
      pfam04968
      Location:364
      CHORD; CHORD
      cl00175
      Location:219273
      alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.
    3. XM_010821853.4XP_010820155.1  integrin beta-1-binding protein 2 isoform X3

      Conserved Domains (2) summary
      pfam04968
      Location:364
      CHORD; CHORD
      cl00175
      Location:219273
      alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.
    4. XM_015461654.3XP_015317140.1  integrin beta-1-binding protein 2 isoform X4

      Conserved Domains (2) summary
      cd06488
      Location:96182
      p23_melusin_like; p23_like domain similar to the C-terminal (tail) domain of vertebrate Melusin and related proteins. Melusin's tail domain interacts with the cytoplasmic domain of beta1-A and beta1-D isoforms of beta1 integrin, it does not bind other integrin beta ...
      pfam04968
      Location:2586
      CHORD; CHORD

    RNA

    1. XR_816942.2 RNA Sequence

    2. XR_816941.2 RNA Sequence

    3. XR_816940.2 RNA Sequence