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    CMKLR2 chemerin chemokine-like receptor 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 509707, updated on 29-Jan-2025

    Summary

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    Official Symbol
    CMKLR2provided by VGNC
    Official Full Name
    chemerin chemokine-like receptor 2provided by VGNC
    Primary source
    VGNC:VGNC:29542
    See related
    BGD:BT14508; Ensembl:ENSBTAG00000061822
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    GPR1
    Orthologs
    human mouse all
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    Genomic context

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    See CMKLR2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (94506505..94557012, complement)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD51 Neighboring gene small nucleolar RNA SNORA41 Neighboring gene eukaryotic translation elongation factor 1 beta 2 Neighboring gene uncharacterized LOC132343216 Neighboring gene zinc finger DBF-type containing 2 Neighboring gene uncharacterized LOC112442953

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables complement receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in complement receptor mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cytosolic calcium ion concentration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    chemerin-like receptor 2
    Names
    G protein-coupled receptor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206545.1 → NP_001193474.1  chemerin-like receptor 2

      See identical proteins and their annotated locations for NP_001193474.1

      Status: VALIDATED

      Source sequence(s)
      BE749356, NKLS02000002
      UniProtKB/TrEMBL
      F1MLK8
      Conserved Domains (1) summary
      cd15119
      Location:39 → 315
      7tmA_GPR1; G protein-coupled receptor 1 for chemerin, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      94506505..94557012 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005202718.5 → XP_005202775.1  chemerin-like receptor 2 isoform X1

      See identical proteins and their annotated locations for XP_005202775.1

      Conserved Domains (1) summary
      cd15119
      Location:109 → 385
      7tmA_GPR1; G protein-coupled receptor 1 for chemerin, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. XM_025000353.2 → XP_024856121.1  chemerin-like receptor 2 isoform X1

      Conserved Domains (1) summary
      cd15119
      Location:109 → 385
      7tmA_GPR1; G protein-coupled receptor 1 for chemerin, member of the class A family of seven-transmembrane G protein-coupled receptors

    3. XM_010802249.4 → XP_010800551.1  chemerin-like receptor 2 isoform X2

      See identical proteins and their annotated locations for XP_010800551.1

      UniProtKB/TrEMBL
      F1MLK8
      Conserved Domains (1) summary
      cd15119
      Location:39 → 315
      7tmA_GPR1; G protein-coupled receptor 1 for chemerin, member of the class A family of seven-transmembrane G protein-coupled receptors

    4. XM_005202723.5 → XP_005202780.1  chemerin-like receptor 2 isoform X2

      See identical proteins and their annotated locations for XP_005202780.1

      UniProtKB/TrEMBL
      F1MLK8
      Related
      ENSBTAP00070004266.1, ENSBTAT00070007238.1
      Conserved Domains (1) summary
      cd15119
      Location:39 → 315
      7tmA_GPR1; G protein-coupled receptor 1 for chemerin, member of the class A family of seven-transmembrane G protein-coupled receptors

    5. XM_005202720.5 → XP_005202777.1  chemerin-like receptor 2 isoform X2

      See identical proteins and their annotated locations for XP_005202777.1

      UniProtKB/TrEMBL
      F1MLK8
      Conserved Domains (1) summary
      cd15119
      Location:39 → 315
      7tmA_GPR1; G protein-coupled receptor 1 for chemerin, member of the class A family of seven-transmembrane G protein-coupled receptors

    6. XM_005202721.5 → XP_005202778.1  chemerin-like receptor 2 isoform X2

      See identical proteins and their annotated locations for XP_005202778.1

      UniProtKB/TrEMBL
      F1MLK8
      Related
      ENSBTAP00070004296.1, ENSBTAT00070007269.1
      Conserved Domains (1) summary
      cd15119
      Location:39 → 315
      7tmA_GPR1; G protein-coupled receptor 1 for chemerin, member of the class A family of seven-transmembrane G protein-coupled receptors

    7. XM_005202722.5 → XP_005202779.1  chemerin-like receptor 2 isoform X2

      See identical proteins and their annotated locations for XP_005202779.1

      UniProtKB/TrEMBL
      F1MLK8
      Related
      ENSBTAP00070004292.1, ENSBTAT00070007265.1
      Conserved Domains (1) summary
      cd15119
      Location:39 → 315
      7tmA_GPR1; G protein-coupled receptor 1 for chemerin, member of the class A family of seven-transmembrane G protein-coupled receptors

    8. XM_005202724.5 → XP_005202781.1  chemerin-like receptor 2 isoform X2

      See identical proteins and their annotated locations for XP_005202781.1

      UniProtKB/TrEMBL
      F1MLK8
      Related
      ENSBTAP00070004294.1, ENSBTAT00070007267.1
      Conserved Domains (1) summary
      cd15119
      Location:39 → 315
      7tmA_GPR1; G protein-coupled receptor 1 for chemerin, member of the class A family of seven-transmembrane G protein-coupled receptors

    9. XM_005202719.5 → XP_005202776.1  chemerin-like receptor 2 isoform X2

      See identical proteins and their annotated locations for XP_005202776.1

      UniProtKB/TrEMBL
      F1MLK8
      Related
      ENSBTAP00070004291.1, ENSBTAT00070007264.1
      Conserved Domains (1) summary
      cd15119
      Location:39 → 315
      7tmA_GPR1; G protein-coupled receptor 1 for chemerin, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein Strain
    Heading Accession and Version

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