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    LOC510377 nuclear body protein SP140-like protein [ Bos taurus (domestic cattle) ]

    Gene ID: 510377, updated on 27-Dec-2024

    Summary

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    Gene symbol
    LOC510377
    Gene description
    nuclear body protein SP140-like protein
    See related
    BGD:BT24881; Ensembl:ENSBTAG00000009664
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    SP140
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    Genomic context

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    See LOC510377 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (118232936..118314093)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene serine/arginine-rich splicing factor 9 Neighboring gene SP110 nuclear body protein Neighboring gene uncharacterized LOC132343343 Neighboring gene SP100 nuclear antigen Neighboring gene SP140 nuclear body protein-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Clone Names

    • MGC140309

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nuclear body protein SP140; nuclear body protein SP140-like protein
    Names
    SP140 nuclear body protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      118232936..118314093
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059879223.1 → XP_059735206.1  nuclear body protein SP140-like protein isoform X22

      UniProtKB/TrEMBL
      A0AAA9TGX1

    2. XM_059879227.1 → XP_059735210.1  nuclear body protein SP140-like protein isoform X24

      UniProtKB/TrEMBL
      A0AAA9TGX1

    3. XM_059879222.1 → XP_059735205.1  nuclear body protein SP140-like protein isoform X22

      UniProtKB/TrEMBL
      A0AAA9TGX1

    4. XM_059879220.1 → XP_059735203.1  nuclear body protein SP140-like protein isoform X22

      UniProtKB/TrEMBL
      A0AAA9TGX1

    5. XM_059879237.1 → XP_059735220.1  nuclear body protein SP140-like protein isoform X26

      UniProtKB/TrEMBL
      A0AAA9S6G8

    6. XM_059879236.1 → XP_059735219.1  nuclear body protein SP140-like protein isoform X25

      UniProtKB/TrEMBL
      A0AAA9S6G8

    7. XM_024981963.2 → XP_024837731.1  nuclear body protein SP140 isoform X29

      UniProtKB/TrEMBL
      A0AAA9S6G8
      Related
      ENSBTAP00000079488.1, ENSBTAT00000130329.1
      Conserved Domains (5) summary
      pfam06390
      Location:202 → 370
      NESP55; Neuroendocrine-specific golgi protein P55 (NESP55)
      cd15626
      Location:618 → 658
      PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components
      pfam01342
      Location:509 → 584
      SAND; SAND domain
      pfam03172
      Location:29 → 127
      HSR; HSR domain
      cl02556
      Location:683 → 784
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    8. XM_059879241.1 → XP_059735224.1  nuclear body protein SP140-like protein isoform X28

      UniProtKB/TrEMBL
      A0AAA9S6G8

    9. XM_024981991.2 → XP_024837759.1  nuclear body protein SP140 isoform X31

      UniProtKB/TrEMBL
      A0AAA9S6G8
      Related
      ENSBTAP00000012738.6, ENSBTAT00000012738.6
      Conserved Domains (4) summary
      cd15626
      Location:591 → 631
      PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components
      pfam01342
      Location:482 → 557
      SAND; SAND domain
      pfam03172
      Location:29 → 127
      HSR; HSR domain
      cl02556
      Location:656 → 757
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    10. XM_059879247.1 → XP_059735230.1  nuclear body protein SP140-like protein isoform X30

      UniProtKB/TrEMBL
      A0AAA9S6G8

    11. XM_024981994.2 → XP_024837762.1  nuclear body protein SP140-like protein isoform X32

      UniProtKB/TrEMBL
      A0AAA9S6G8
      Conserved Domains (4) summary
      cd15626
      Location:563 → 603
      PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components
      pfam01342
      Location:454 → 529
      SAND; SAND domain
      pfam03172
      Location:29 → 127
      HSR; HSR domain
      cl02556
      Location:628 → 729
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    12. XM_059879238.1 → XP_059735221.1  nuclear body protein SP140 isoform X27

    13. XM_059879182.1 → XP_059735165.1  nuclear body protein SP140-like protein isoform X7

      UniProtKB/TrEMBL
      A0AAA9TGX1

    14. XM_059879173.1 → XP_059735156.1  nuclear body protein SP140-like protein isoform X3

      UniProtKB/TrEMBL
      A0AAA9TGX1

    15. XM_059879174.1 → XP_059735157.1  nuclear body protein SP140-like protein isoform X4

      UniProtKB/TrEMBL
      A0AAA9TGX1

    16. XM_059879202.1 → XP_059735185.1  nuclear body protein SP140-like protein isoform X14

      UniProtKB/TrEMBL
      A0AAA9TGX1

    17. XM_059879171.1 → XP_059735154.1  nuclear body protein SP140-like protein isoform X2

      UniProtKB/TrEMBL
      A0AAA9TGX1

    18. XM_059879164.1 → XP_059735147.1  nuclear body protein SP140-like protein isoform X1

      UniProtKB/TrEMBL
      A0AAA9TGX1

    19. XM_059879193.1 → XP_059735176.1  nuclear body protein SP140-like protein isoform X12

      UniProtKB/TrEMBL
      A0AAA9S6G8

    20. XM_059879199.1 → XP_059735182.1  nuclear body protein SP140-like protein isoform X13

      UniProtKB/TrEMBL
      A0AAA9TGX1

    21. XM_059879184.1 → XP_059735167.1  nuclear body protein SP140-like protein isoform X8

      UniProtKB/TrEMBL
      A0AAA9TGX1

    22. XM_059879179.1 → XP_059735162.1  nuclear body protein SP140-like protein isoform X6

      UniProtKB/TrEMBL
      A0AAA9TGX1

    23. XM_059879217.1 → XP_059735200.1  nuclear body protein SP140-like protein isoform X20

      UniProtKB/TrEMBL
      A0AAA9TGX1

    24. XM_059879213.1 → XP_059735196.1  nuclear body protein SP140-like protein isoform X17

      UniProtKB/TrEMBL
      A0AAA9S6G8

    25. XM_024981877.2 → XP_024837645.1  nuclear body protein SP140-like protein isoform X9

      UniProtKB/TrEMBL
      A0AAA9TGX1
      Conserved Domains (5) summary
      PHA03169
      Location:379 → 562
      PHA03169; hypothetical protein; Provisional
      cd15626
      Location:782 → 822
      PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components
      pfam01342
      Location:673 → 748
      SAND; SAND domain
      pfam03172
      Location:139 → 237
      HSR; HSR domain
      cl02556
      Location:847 → 948
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    26. XM_059879187.1 → XP_059735170.1  nuclear body protein SP140-like protein isoform X10

      UniProtKB/TrEMBL
      A0AAA9TGX1

    27. XM_059879204.1 → XP_059735187.1  nuclear body protein SP140-like protein isoform X15

      UniProtKB/TrEMBL
      A0AAA9TGX1

    28. XM_059879177.1 → XP_059735160.1  nuclear body protein SP140-like protein isoform X5

      UniProtKB/TrEMBL
      A0AAA9S6G8

    29. XM_059879216.1 → XP_059735199.1  nuclear body protein SP140-like protein isoform X19

      UniProtKB/TrEMBL
      A0AAA9S6G8

    30. XM_024981907.2 → XP_024837675.1  nuclear body protein SP140-like protein isoform X16

      UniProtKB/TrEMBL
      A0AAA9TGX1
      Conserved Domains (4) summary
      cd15626
      Location:752 → 792
      PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components
      pfam01342
      Location:643 → 718
      SAND; SAND domain
      pfam03172
      Location:139 → 237
      HSR; HSR domain
      cl02556
      Location:817 → 918
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    31. XM_059879189.1 → XP_059735172.1  nuclear body protein SP140-like protein isoform X11

      UniProtKB/TrEMBL
      A0AAA9S6G8

    32. XM_059879219.1 → XP_059735202.1  nuclear body protein SP140-like protein isoform X21

      UniProtKB/TrEMBL
      A0AAA9S6G8

    33. XM_059879214.1 → XP_059735197.1  nuclear body protein SP140-like protein isoform X18

      UniProtKB/TrEMBL
      A0AAA9S6G8

    34. XM_024981934.2 → XP_024837702.1  nuclear body protein SP140 isoform X23

      UniProtKB/TrEMBL
      A0AAA9S6G8
      Conserved Domains (4) summary
      cd15626
      Location:701 → 741
      PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components
      pfam01342
      Location:592 → 667
      SAND; SAND domain
      pfam03172
      Location:139 → 237
      HSR; HSR domain
      cl02556
      Location:766 → 867
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    35. XM_059879231.1 → XP_059735214.1  nuclear body protein SP140-like protein isoform X24

      UniProtKB/TrEMBL
      A0AAA9TGX1

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001075447.1: Suppressed sequence

      Description
      NM_001075447.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from human: SP140 (GeneID:11262).
    Nucleotide Protein Strain
    Heading Accession and Version

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