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    RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase [ Bos taurus (domestic cattle) ]

    Gene ID: 540195, updated on 29-Jan-2025

    Summary

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    Official Symbol
    RNF19Aprovided by VGNC
    Official Full Name
    ring finger protein 19A, RBR E3 ubiquitin protein ligaseprovided by VGNC
    Primary source
    VGNC:VGNC:34044
    See related
    BGD:BT16656; Ensembl:ENSBTAG00000017833
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See RNF19A in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 14 NC_037341.1 (64047881..64103385)

    Chromosome 14 - NC_037341.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 46 Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene uncharacterized LOC112449540 Neighboring gene sperm associated antigen 1 Neighboring gene RNA polymerase II, I and III subunit K

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037341.1 Chromosome 14 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin conjugating enzyme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase RNF19A
    NP_001178260.1
    XP_010810472.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191331.1 → NP_001178260.1  E3 ubiquitin-protein ligase RNF19A

      See identical proteins and their annotated locations for NP_001178260.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000014
      UniProtKB/TrEMBL
      E1BIP5
      Conserved Domains (4) summary
      smart00647
      Location:199 → 264
      IBR; In Between Ring fingers
      pfam01485
      Location:297 → 335
      IBR; IBR domain, a half RING-finger domain
      cd16775
      Location:131 → 185
      RING-HC_RBR_RNF19A; RING finger, HC subclass, found in RING finger protein 19A (RNF19A) and similar proteins
      cl00570
      Location:361 → 450
      AzlC; AzlC protein

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037341.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      64047881..64103385
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010812170.4 → XP_010810472.1  E3 ubiquitin-protein ligase RNF19A isoform X1

      See identical proteins and their annotated locations for XP_010810472.1

      UniProtKB/TrEMBL
      E1BIP5
      Related
      ENSBTAP00070010625.1, ENSBTAT00070018178.1
      Conserved Domains (4) summary
      smart00647
      Location:199 → 264
      IBR; In Between Ring fingers
      pfam01485
      Location:297 → 335
      IBR; IBR domain, a half RING-finger domain
      cd16775
      Location:131 → 185
      RING-HC_RBR_RNF19A; RING finger, HC subclass, found in RING finger protein 19A (RNF19A) and similar proteins
      cl00570
      Location:361 → 450
      AzlC; AzlC protein
    Nucleotide Protein Strain
    Heading Accession and Version

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