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    TPCN2 two pore segment channel 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 516679, updated on 29-Jan-2025

    Summary

    Official Symbol
    TPCN2provided by VGNC
    Official Full Name
    two pore segment channel 2provided by VGNC
    Primary source
    VGNC:VGNC:36244
    See related
    Ensembl:ENSBTAG00000015183
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
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    Genomic context

    See TPCN2 in Genome Data Viewer
    Location:
    chromosome: 29
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 29 NC_037356.1 (46382164..46413290)

    Chromosome 29 - NC_037356.1Genomic Context describing neighboring genes Neighboring gene mas-related G-protein coupled receptor member D Neighboring gene MAS related GPR family member F Neighboring gene small integral membrane protein 38 Neighboring gene uncharacterized LOC112444899

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037356.1 Chromosome 29 Reference ARS-UCD2.0 Primary Assembly

    Expression

    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    General gene information

    Gene Ontology Provided by RefSeq

    Component Evidence Code Pubs
    located_in lysosomal membrane PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192451.2NP_001179380.1  two pore channel protein 2

      See identical proteins and their annotated locations for NP_001179380.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000029
      UniProtKB/TrEMBL
      A0A3Q1MD89
      Related
      ENSBTAP00070041699.1, ENSBTAT00070068241.1
      Conserved Domains (1) summary
      pfam00520
      Location:458696
      Ion_trans; Ion transport protein

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037356.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      46382164..46413290
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024987148.2XP_024842916.1  two pore channel protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MD89
      Related
      ENSBTAP00070041715.1, ENSBTAT00070068266.1
      Conserved Domains (1) summary
      pfam00520
      Location:458723
      Ion_trans; Ion transport protein
    2. XM_024987147.2XP_024842915.1  two pore channel protein 2 isoform X1

      UniProtKB/TrEMBL
      E1BIB9
      Conserved Domains (1) summary
      pfam00520
      Location:110342
      Ion_trans; Ion transport protein
    3. XM_024987149.2XP_024842917.1  two pore channel protein 2 isoform X3

      UniProtKB/TrEMBL
      E1BIB9
      Conserved Domains (1) summary
      pfam00520
      Location:83315
      Ion_trans; Ion transport protein
    4. XM_015461347.3XP_015316833.1  two pore channel protein 2 isoform X5

      UniProtKB/TrEMBL
      E1BIB9
      Conserved Domains (2) summary
      pfam00520
      Location:147342
      Ion_trans; Ion transport protein
      pfam15671
      Location:897
      PRR18; Proline-rich protein family 18
    5. XM_059882926.1XP_059738909.1  two pore channel protein 2 isoform X7

      UniProtKB/TrEMBL
      A0A3Q1N2G9
    6. XM_059882927.1XP_059738910.1  two pore channel protein 2 isoform X9

      UniProtKB/TrEMBL
      A0AAA9SQW5
    7. XM_010821240.4XP_010819542.1  two pore channel protein 2 isoform X8

      UniProtKB/TrEMBL
      A0A3Q1N2G9
      Conserved Domains (2) summary
      pfam00520
      Location:147342
      Ion_trans; Ion transport protein
      pfam15671
      Location:897
      PRR18; Proline-rich protein family 18
    8. XM_059882925.1XP_059738908.1  two pore channel protein 2 isoform X6

      UniProtKB/TrEMBL
      A0A3Q1MGT1
    9. XM_024987150.2XP_024842918.1  two pore channel protein 2 isoform X4

      UniProtKB/TrEMBL
      A0AAA9T0Y1
      Conserved Domains (1) summary
      pfam00520
      Location:76308
      Ion_trans; Ion transport protein
    10. XM_024987151.2XP_024842919.1  two pore channel protein 2 isoform X10

      Conserved Domains (1) summary
      pfam00520
      Location:15145
      Ion_trans; Ion transport protein
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