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    LOC789205 immunoglobulin lambda-1 light chain-like [ Bos taurus (domestic cattle) ]

    Gene ID: 789205, updated on 1-Jan-2025

    Summary

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    Gene symbol
    LOC789205
    Gene description
    immunoglobulin lambda-1 light chain-like
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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    Genomic context

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    See LOC789205 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 17 NC_037344.1 (70689595..71137767)

    Chromosome 17 - NC_037344.1Genomic Context describing neighboring genes Neighboring gene immunoglobulin lambda variable 1-40-like Neighboring gene immunoglobulin lambda-1 light chain Neighboring gene immunoglobulin light chain variable region Neighboring gene immunoglobulin lambda variable 5-39-like Neighboring gene immunoglobulin lambda variable 1-40-like Neighboring gene immunoglobulin lambda variable 1-40-like Neighboring gene immunoglobulin lambda variable 1-40-like Neighboring gene immunoglobulin lambda variable 1-40-like Neighboring gene immunoglobulin lambda variable 1-40-like Neighboring gene immunoglobulin lambda light chain variable region Neighboring gene adenylosuccinate synthetase isozyme 2-like Neighboring gene probable non-functional immunoglobulin lambda variable 5-48 Neighboring gene immunoglobulin lambda variable 1-40-like Neighboring gene adenylosuccinate synthetase isozyme 2-like Neighboring gene probable non-functional immunoglobulin lambda variable 5-48 Neighboring gene immunoglobulin lambda variable 1-40-like Neighboring gene immunoglobulin lambda variable 1-40-like Neighboring gene immunoglobulin lambda variable 8-61-like Neighboring gene immunoglobulin lambda variable 1-40-like Neighboring gene uncharacterized LOC132342659 Neighboring gene immunoglobulin lambda variable 1-40-like Neighboring gene immunoglobulin lambda variable 1-40-like Neighboring gene immunoglobulin lambda variable 2-23-like Neighboring gene transfer RNA serine (anticodon GGA) Neighboring gene immunoglobulin lambda variable 1-40-like Neighboring gene immunoglobulin lambda variable 1-40-like Neighboring gene immunoglobulin lambda variable 1-40-like Neighboring gene melanoma antigen preferentially expressed in tumors-like Neighboring gene zinc finger protein 280B Neighboring gene zinc finger protein 280A Neighboring gene immunoglobulin lambda variable 3-19-like Neighboring gene immunoglobulin lambda variable 3-25-like Neighboring gene immunoglobulin lambda variable 3-25 Neighboring gene immunoglobulin lambda constant 1 Neighboring gene immunoglobulin lambda constant 2-like Neighboring gene immunoglobulin lambda constant 1-like Neighboring gene Ig heavy chain Mem5-like Neighboring gene immunoglobulin lambda constant 1-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Detection of new allotypic variants of bovine λ-light chain constant regions in different cattle breeds. Diesterbeck US, et al. Dev Comp Immunol, 2012 Jan. PMID 21741991
    2. Bos taurus genome sequence reveals the assortment of immunoglobulin and surrogate light chain genes in domestic cattle. Ekman A, et al. BMC Immunol, 2009 Apr 30. PMID 19405939, Free PMC Article
    3. Exceptionally long CDR3H region with multiple cysteine residues in functional bovine IgM antibodies. Saini SS, et al. Eur J Immunol, 1999 Aug. PMID 10458755
    4. B lymphopoiesis is characterized by pre-B cell marker gene expression in fetal cattle and declines in adults. Ekman A, et al. Dev Comp Immunol, 2012 May. PMID 22210545
    5. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC151892

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immunoglobulin production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    immunoglobulin lambda-1 light chain-like
    Names
    Vlambda1.1a
    immunoglobulin lambda chain variable region
    immunoglobulin light chain variable region

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083800.1 → NP_001077269.1  immunoglobulin lambda-1 light chain-like precursor

      See identical proteins and their annotated locations for NP_001077269.1

      Status: PROVISIONAL

      Source sequence(s)
      BC134589
      UniProtKB/TrEMBL
      A4IFI0, Q1RMN8
      Conserved Domains (3) summary
      cd07699
      Location:135 → 231
      IgC_L; Immunoglobulin Constant domain
      smart00410
      Location:26 → 128
      IG_like; Immunoglobulin like
      cl11960
      Location:29 → 128
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037344.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      70689595..71137767
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059876184.1 → XP_059732167.1  immunoglobulin lambda-1 light chain-like isoform X1

      UniProtKB/TrEMBL
      A5PK72

    2. XM_059876185.1 → XP_059732168.1  immunoglobulin lambda-1 light chain-like isoform X2

      UniProtKB/TrEMBL
      A6QM09
    Nucleotide Protein Strain
    Heading Accession and Version

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