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    CENPA centromere protein A [ Bos taurus (domestic cattle) ]

    Gene ID: 613898, updated on 27-Dec-2024

    Summary

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    Gene symbol
    CENPA
    Gene description
    centromere protein A
    See related
    BGD:BT15430; Ensembl:ENSBTAG00000023938
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CENPA in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (72791048..72798612, complement)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA62/SNORA6 family Neighboring gene microtubule associated protein RP/EB family member 3 Neighboring gene dihydropyrimidinase like 5 Neighboring gene solute carrier family 35 member F6 Neighboring gene potassium two pore domain channel subfamily K member 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Human CENP-A contains a histone H3 related histone fold domain that is required for targeting to the centromere. Sullivan KF, et al. J Cell Biol, 1994 Nov. PMID 7962047, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of nucleosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone H3-like centromeric protein A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205380.1 → NP_001192309.1  histone H3-like centromeric protein A

      See identical proteins and their annotated locations for NP_001192309.1

      Status: VALIDATED

      Source sequence(s)
      BC116010, EE235151
      UniProtKB/TrEMBL
      F1MLV4
      Related
      ENSBTAP00000032858.4, ENSBTAT00000032931.5
      Conserved Domains (2) summary
      pfam00125
      Location:1 → 131
      Histone; Core histone H2A/H2B/H3/H4
      cl23735
      Location:32 → 132
      H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      72791048..72798612 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005213047.5 → XP_005213104.1  histone H3-like centromeric protein A isoform X1

      See identical proteins and their annotated locations for XP_005213104.1

      UniProtKB/TrEMBL
      F1MLV4
      Conserved Domains (2) summary
      pfam00125
      Location:1 → 131
      Histone; Core histone H2A/H2B/H3/H4
      cl23735
      Location:32 → 132
      H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...

    2. XM_005213046.5 → XP_005213103.1  histone H3-like centromeric protein A isoform X1

      See identical proteins and their annotated locations for XP_005213103.1

      UniProtKB/TrEMBL
      F1MLV4
      Conserved Domains (2) summary
      pfam00125
      Location:1 → 131
      Histone; Core histone H2A/H2B/H3/H4
      cl23735
      Location:32 → 132
      H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...

    3. XM_010810245.4 → XP_010808547.1  histone H3-like centromeric protein A isoform X1

      See identical proteins and their annotated locations for XP_010808547.1

      UniProtKB/TrEMBL
      F1MLV4
      Conserved Domains (2) summary
      pfam00125
      Location:1 → 131
      Histone; Core histone H2A/H2B/H3/H4
      cl23735
      Location:32 → 132
      H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...
    Nucleotide Protein Strain
    Heading Accession and Version

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