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    RUSC1 RUN and SH3 domain containing 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 100125592, updated on 27-Dec-2024

    Summary

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    Official Symbol
    RUSC1provided by VGNC
    Official Full Name
    RUN and SH3 domain containing 1provided by VGNC
    Primary source
    VGNC:VGNC:106909
    See related
    BGD:BT19744; Ensembl:ENSBTAG00000054061
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See RUSC1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (15300717..15310967, complement)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene death associated protein 3 Neighboring gene ASH1 like histone lysine methyltransferase Neighboring gene transfer RNA glutamine (anticodon CUG) Neighboring gene farnesyl diphosphate synthase Neighboring gene pyruvate kinase L/R

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC148826

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RUN and SH3 domain-containing protein 1; AP-4 complex accessory subunit RUSC1
    Names
    nesca

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      15300717..15310967 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003585837.6 → XP_003585885.2  AP-4 complex accessory subunit RUSC1 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1M0B1
      Related
      ENSBTAP00000061397.1, ENSBTAT00000067857.2
      Conserved Domains (2) summary
      pfam02759
      Location:670 → 780
      RUN; RUN domain
      cl17036
      Location:988 → 1039
      SH3; Src Homology 3 domain superfamily

    2. XM_005203788.5 → XP_005203845.1  AP-4 complex accessory subunit RUSC1 isoform X1

      Conserved Domains (2) summary
      pfam02759
      Location:672 → 782
      RUN; RUN domain
      cl17036
      Location:990 → 1041
      SH3; Src Homology 3 domain superfamily

    3. XM_005203790.5 → XP_005203847.1  AP-4 complex accessory subunit RUSC1 isoform X4

      Conserved Domains (2) summary
      pfam02759
      Location:533 → 643
      RUN; RUN domain
      cl17036
      Location:851 → 902
      SH3; Src Homology 3 domain superfamily

    4. XM_005203789.5 → XP_005203846.1  AP-4 complex accessory subunit RUSC1 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1N0F6
      Related
      ENSBTAP00000062160.2, ENSBTAT00000079102.2
      Conserved Domains (2) summary
      pfam02759
      Location:535 → 645
      RUN; RUN domain
      cl17036
      Location:853 → 904
      SH3; Src Homology 3 domain superfamily

    5. XM_015462446.3 → XP_015317932.1  AP-4 complex accessory subunit RUSC1 isoform X5

      Conserved Domains (2) summary
      pfam02759
      Location:63 → 173
      RUN; RUN domain
      cl17036
      Location:381 → 432
      SH3; Src Homology 3 domain superfamily

    6. XM_005203791.5 → XP_005203848.1  AP-4 complex accessory subunit RUSC1 isoform X6

      UniProtKB/TrEMBL
      A8E4R3
      Conserved Domains (2) summary
      pfam02759
      Location:61 → 171
      RUN; RUN domain
      cl17036
      Location:379 → 430
      SH3; Src Homology 3 domain superfamily

    7. XM_010802958.4 → XP_010801260.1  AP-4 complex accessory subunit RUSC1 isoform X5

      Conserved Domains (2) summary
      pfam02759
      Location:63 → 173
      RUN; RUN domain
      cl17036
      Location:381 → 432
      SH3; Src Homology 3 domain superfamily

    8. XM_015462453.2 → XP_015317939.1  AP-4 complex accessory subunit RUSC1 isoform X6

      UniProtKB/TrEMBL
      A8E4R3
      Conserved Domains (2) summary
      pfam02759
      Location:61 → 171
      RUN; RUN domain
      cl17036
      Location:379 → 430
      SH3; Src Homology 3 domain superfamily

    9. XM_015462443.2 → XP_015317929.1  AP-4 complex accessory subunit RUSC1 isoform X5

      Conserved Domains (2) summary
      pfam02759
      Location:63 → 173
      RUN; RUN domain
      cl17036
      Location:381 → 432
      SH3; Src Homology 3 domain superfamily

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001105041.1: Suppressed sequence

      Description
      NM_001105041.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from human: RUSC1 (GeneID:23623).
    Nucleotide Protein Strain
    Heading Accession and Version

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