NPPC natriuretic peptide C [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: NPPCprovided by VGNC
Official Full Name: natriuretic peptide Cprovided by VGNC
Primary source: VGNC:VGNC:32212
See related: BGD:BT10914; Ensembl:ENSBTAG00000003253
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	2	NC_037329.1 (119585593..119590246, complement)

Chromosome 2 - NC_037329.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data suggest natriuretic peptide precursor C (NPPC) can regulate oogenesis/gap junction mediated communication between oocytes and cumulus cells; here, NPPC is used in non-pharmacological coordination of meiotic prophase in vitro oocyte maturation.
Title: Natriuretic peptide precursor C delays meiotic resumption and sustains gap junction-mediated communication in bovine cumulus-enclosed oocytes.

Submit: New GeneRIF Correction

General gene information

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Markers

NPPC (e-PCR), detects polymorphism
- UniSTS:253992

NoName (e-PCR)
- UniSTS:480745

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables hormone activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cGMP biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in receptor guanylyl cyclase signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: C-type natriuretic peptide

Names: SVSP15; natriuretic peptide precursor C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.