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    CHRNG cholinergic receptor nicotinic gamma subunit [ Bos taurus (domestic cattle) ]

    Gene ID: 281689, updated on 1-Jan-2025

    Summary

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    Official Symbol
    CHRNGprovided by VGNC
    Official Full Name
    cholinergic receptor nicotinic gamma subunitprovided by VGNC
    Primary source
    VGNC:VGNC:27336
    See related
    Ensembl:ENSBTAG00000045943
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CHRNG in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (120180193..120185721)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene serine protease 56 Neighboring gene cholinergic receptor nicotinic delta subunit Neighboring gene eukaryotic translation initiation factor 4E family member 2 Neighboring gene uncharacterized LOC112443174 Neighboring gene uncharacterized LOC101906781 Neighboring gene inward rectifier potassium channel 13-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Primary structure of gamma subunit precursor of calf-muscle acetylcholine receptor deduced from the cDNA sequence. Takai T, et al. Eur J Biochem, 1984 Aug 15. PMID 6547904
    2. Primary structure of delta subunit precursor of calf muscle acetylcholine receptor deduced from cDNA sequence. Kubo T, et al. Eur J Biochem, 1985 May 15. PMID 3838938
    3. Molecular distinction between fetal and adult forms of muscle acetylcholine receptor. Mishina M, et al. Nature, 1986 May 22-28. PMID 2423878
    4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables acetylcholine-gated monoatomic cation-selective channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    acetylcholine receptor subunit gamma
    Names
    acetylcholine receptor gamma-subunit
    cholinergic receptor, nicotinic, gamma (muscle)
    cholinergic receptor, nicotinic, gamma polypeptide

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174273.2 → NP_776698.1  acetylcholine receptor subunit gamma precursor

      See identical proteins and their annotated locations for NP_776698.1

      Status: PROVISIONAL

      Source sequence(s)
      M28307
      UniProtKB/Swiss-Prot
      P13536
      UniProtKB/TrEMBL
      A0AAA9TAU4
      Related
      ENSBTAP00000048242.2, ENSBTAT00000053164.3
      Conserved Domains (3) summary
      TIGR00860
      Location:5 → 497
      LIC; Cation transporter family protein
      pfam02931
      Location:26 → 241
      Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
      pfam02932
      Location:248 → 494
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      120180193..120185721
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P13536.1 GenPept UniProtKB/Swiss-Prot:P13536

    Gene LinkOut

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