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    FLT3LG fms related receptor tyrosine kinase 3 ligand [ Bos taurus (domestic cattle) ]

    Gene ID: 282233, updated on 27-Dec-2024

    Summary

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    Official Symbol
    FLT3LGprovided by VGNC
    Official Full Name
    fms related receptor tyrosine kinase 3 ligandprovided by VGNC
    Primary source
    VGNC:VGNC:29043
    See related
    BGD:BT30117; Ensembl:ENSBTAG00000038045
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See FLT3LG in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (55929632..55939492)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene golgi associated olfactory signaling regulator Neighboring gene solute carrier family 17 member 7 Neighboring gene PIH1 domain containing 1 Neighboring gene aldehyde dehydrogenase 16 family member A1 Neighboring gene small nucleolar RNA Z195/SNORD33/SNORD32 family Neighboring gene small nucleolar RNA Z195/SNORD33/SNORD32 family Neighboring gene ribosomal protein L13a

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Identification of fetal liver tyrosine kinase 3 (flt3) ligand domain required for receptor binding and function using naturally occurring ligand isoforms. Mwangi W, et al. J Immunol, 2000 Dec 15. PMID 11120823
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cytokine activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables receptor tyrosine kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    fms-related tyrosine kinase 3 ligand
    Names
    fms related tyrosine kinase 3 ligand
    fms-like tyrosine kinase 3 ligand

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_181030.2 → NP_851373.1  fms-related tyrosine kinase 3 ligand precursor

      See identical proteins and their annotated locations for NP_851373.1

      Status: PROVISIONAL

      Source sequence(s)
      AF282985
      UniProtKB/TrEMBL
      F6RZ26, Q9GKE0
      Related
      ENSBTAP00000006962.4, ENSBTAT00000006962.5
      Conserved Domains (1) summary
      pfam02947
      Location:30 → 160
      Flt3_lig; flt3 ligand

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      55929632..55939492
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005219164.5 → XP_005219221.1  fms-related tyrosine kinase 3 ligand isoform X1

      See identical proteins and their annotated locations for XP_005219221.1

      UniProtKB/TrEMBL
      F6RZ26, Q8WNW1
      Conserved Domains (1) summary
      pfam02947
      Location:30 → 160
      Flt3_lig; flt3 ligand

    2. XM_005219163.5 → XP_005219220.1  fms-related tyrosine kinase 3 ligand isoform X1

      See identical proteins and their annotated locations for XP_005219220.1

      UniProtKB/TrEMBL
      F6RZ26, Q8WNW1
      Conserved Domains (1) summary
      pfam02947
      Location:30 → 160
      Flt3_lig; flt3 ligand

    3. XM_005219166.5 → XP_005219223.1  fms-related tyrosine kinase 3 ligand isoform X2

      See identical proteins and their annotated locations for XP_005219223.1

      UniProtKB/TrEMBL
      A2VE24, Q9GKD9
      Conserved Domains (1) summary
      pfam02947
      Location:30 → 142
      Flt3_lig; flt3 ligand
    Nucleotide Protein Strain
    Heading Accession and Version

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