GRO1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) [Bos taurus (domestic cattle)] - Gene

Summary

Gene symbol: GRO1
Gene description: chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
See related: Ensembl:ENSBTAG00000037558
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: GRO2; GROB; GROX; MGSA; CXCL1
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 6

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	6	NC_037333.1 (89072989..89075128)

Chromosome 6 - NC_037333.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

GROX-1 (e-PCR)
- UniSTS:251578

GRO1-1 (e-PCR), detects polymorphism
- UniSTS:251589

CXCL1 (e-PCR)
- UniSTS:519154

CXCL2 (e-PCR)
- UniSTS:278260

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables chemokine activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in defense response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: growth-regulated protein homolog alpha

Names: GRO-alpha; GRO-beta; GRO1 oncogene (melanoma growth stimulating activity, alpha); GRO2, growth related gene 2 (GRO2 oncogene); growth related gene 1; growth related oncogene X; growth-regulated protein homolog beta

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_175700.2 → NP_783631.2 growth-regulated protein homolog alpha precursor

Status: VALIDATED

Source sequence(s)

NKLS02000006

UniProtKB/Swiss-Prot

O46677

Related

ENSBTAP00000022366.5, ENSBTAT00000022366.7

Conserved Domains (1) summary

cd00273
Location:37 → 99

Chemokine_CXC; Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members ...