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    KAT6B lysine acetyltransferase 6B [ Bos taurus (domestic cattle) ]

    Gene ID: 535403, updated on 1-Jan-2025

    Summary

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    Official Symbol
    KAT6Bprovided by VGNC
    Official Full Name
    lysine acetyltransferase 6Bprovided by VGNC
    Primary source
    VGNC:VGNC:30402
    See related
    BGD:BT25348; Ensembl:ENSBTAG00000002920
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    MYST4
    Orthologs
    human mouse all
    NEW
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    Genomic context

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    See KAT6B in Genome Data Viewer
    Location:
    chromosome: 28
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 28 NC_037355.1 (30630312..30812400)

    Chromosome 28 - NC_037355.1Genomic Context describing neighboring genes Neighboring gene adaptor related protein complex 3 subunit mu 1 Neighboring gene adenosine kinase Neighboring gene axin interactor, dorsalization-associated protein-like Neighboring gene microRNA mir-584-3 Neighboring gene dual specificity phosphatase 29 Neighboring gene sterile alpha motif domain containing 8 Neighboring gene dual specificity phosphatase 13

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037355.1 Chromosome 28 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Investigation of MYST4 histone acetyltransferase and its involvement in mammalian gametogenesis. McGraw S, et al. BMC Dev Biol, 2007 Nov 2. PMID 17980037, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. MYST4 may contribute to important and specific acetylation events occurring during gametes and embryo development
      Title: Investigation of MYST4 histone acetyltransferase and its involvement in mammalian gametogenesis.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nucleosome assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MOZ/MORF histone acetyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of nucleosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone acetyltransferase KAT6B
    Names
    K(lysine) acetyltransferase 6B
    MYST histone acetyltransferase (monocytic leukemia) 4
    XP_002698931.1
    XP_005226566.1
    XP_005226567.1
    XP_005226568.1
    XP_024842641.1
    XP_059738663.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037355.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      30630312..30812400
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024986873.2 → XP_024842641.1  histone acetyltransferase KAT6B isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LU60
      Conserved Domains (5) summary
      smart00526
      Location:113 → 167
      H15; Domain in histone families 1 and 5
      cd15527
      Location:271 → 317
      PHD2_KAT6A_6B; PHD finger 2 found in monocytic leukemia zinc-finger protein (MOZ) and its factor (MORF)
      cd15618
      Location:212 → 269
      PHD1_MOZ_MORF; PHD finger 1 found in monocytic leukemia zinc-finger protein (MOZ) and its factor (MORF)
      pfam01271
      Location:1216 → 1503
      Granin; Granin (chromogranin or secretogranin)
      cl27485
      Location:721 → 989
      MOZ_SAS; MOZ/SAS family

    2. XM_005226509.5 → XP_005226566.1  histone acetyltransferase KAT6B isoform X1

      See identical proteins and their annotated locations for XP_005226566.1

      UniProtKB/TrEMBL
      A0A3Q1LU60
      Conserved Domains (5) summary
      smart00526
      Location:113 → 167
      H15; Domain in histone families 1 and 5
      cd15527
      Location:271 → 317
      PHD2_KAT6A_6B; PHD finger 2 found in monocytic leukemia zinc-finger protein (MOZ) and its factor (MORF)
      cd15618
      Location:212 → 269
      PHD1_MOZ_MORF; PHD finger 1 found in monocytic leukemia zinc-finger protein (MOZ) and its factor (MORF)
      pfam01271
      Location:1216 → 1503
      Granin; Granin (chromogranin or secretogranin)
      cl27485
      Location:721 → 989
      MOZ_SAS; MOZ/SAS family

    3. XM_002698885.7 → XP_002698931.1  histone acetyltransferase KAT6B isoform X1

      See identical proteins and their annotated locations for XP_002698931.1

      UniProtKB/TrEMBL
      A0A3Q1LU60
      Conserved Domains (5) summary
      smart00526
      Location:113 → 167
      H15; Domain in histone families 1 and 5
      cd15527
      Location:271 → 317
      PHD2_KAT6A_6B; PHD finger 2 found in monocytic leukemia zinc-finger protein (MOZ) and its factor (MORF)
      cd15618
      Location:212 → 269
      PHD1_MOZ_MORF; PHD finger 1 found in monocytic leukemia zinc-finger protein (MOZ) and its factor (MORF)
      pfam01271
      Location:1216 → 1503
      Granin; Granin (chromogranin or secretogranin)
      cl27485
      Location:721 → 989
      MOZ_SAS; MOZ/SAS family

    4. XM_005226510.5 → XP_005226567.1  histone acetyltransferase KAT6B isoform X2

      See identical proteins and their annotated locations for XP_005226567.1

      Conserved Domains (4) summary
      smart00526
      Location:113 → 167
      H15; Domain in histone families 1 and 5
      cd15527
      Location:271 → 317
      PHD2_KAT6A_6B; PHD finger 2 found in monocytic leukemia zinc-finger protein (MOZ) and its factor (MORF)
      cl22851
      Location:212 → 270
      PHD_SF; PHD finger superfamily
      cl27485
      Location:538 → 806
      MOZ_SAS; MOZ/SAS family

    5. XM_005226511.5 → XP_005226568.1  histone acetyltransferase KAT6B isoform X3

      See identical proteins and their annotated locations for XP_005226568.1

      Related
      ENSBTAP00000003798.6, ENSBTAT00000003798.6
      Conserved Domains (4) summary
      smart00526
      Location:113 → 167
      H15; Domain in histone families 1 and 5
      cd15527
      Location:271 → 317
      PHD2_KAT6A_6B; PHD finger 2 found in monocytic leukemia zinc-finger protein (MOZ) and its factor (MORF)
      cl22851
      Location:212 → 270
      PHD_SF; PHD finger superfamily
      cl27485
      Location:429 → 697
      MOZ_SAS; MOZ/SAS family

    6. XM_059882680.1 → XP_059738663.1  histone acetyltransferase KAT6B isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LU60
      Related
      ENSBTAP00000060655.1, ENSBTAT00000086015.2
    Nucleotide Protein Strain
    Heading Accession and Version

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