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    CG18324 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36568, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG18324provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033905
    Locus tag
    Dmel_CG18324
    See related
    AllianceGenome:FB:FBgn0033905
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG18324
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in mitochondrial transmembrane transport. Predicted to be located in mitochondrial inner membrane. Is expressed in adult head and organism. Orthologous to several human genes including SLC25A35 (solute carrier family 25 member 35). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG18324 in Genome Data Viewer
    Location:
    50E1-50E1; 2-69 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (14168786..14170233)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (10056291..10057738)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 3 subunit m Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44368 Neighboring gene Receptor expression enhancing protein B Neighboring gene mitochondrial ribosomal protein S16 Neighboring gene combgap

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Reliance of Wolbachia on High Rates of Host Proteolysis Revealed by a Genome-Wide RNAi Screen of Drosophila Cells. White PM, et al. Genetics, 2017 Apr. PMID 28159754, Free PMC Article
    2. Drosophila melanogaster Mitochondrial Carriers: Similarities and Differences with the Human Carriers. Curcio R, et al. Int J Mol Sci, 2020 Aug 22. PMID 32842667, Free PMC Article
    3. Phylogenetic Analysis Guides Transporter Protein Deorphanization: A Case Study of the SLC25 Family of Mitochondrial Metabolite Transporters. Byrne KL, et al. Biomolecules, 2023 Aug 28. PMID 37759714, Free PMC Article
    4. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
    5. Transcriptomic analysis of inbreeding depression in cold-sensitive Drosophila melanogaster shows upregulation of the immune response. Vermeulen CJ, et al. J Evol Biol, 2013 Sep. PMID 23944235

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial transmembrane transport TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG18324-PA
    CG18324-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      14168786..14170233
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137091.4 → NP_610935.1  uncharacterized protein Dmel_CG18324, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610935.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K2Y2
      Related
      FBpp0086653
      Conserved Domains (1) summary
      pfam00153
      Location:96 → 188
      Mito_carr; Mitochondrial carrier protein

    2. NM_166033.3 → NP_725361.1  uncharacterized protein Dmel_CG18324, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725361.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z9M0
      Related
      FBpp0086652
      Conserved Domains (2) summary
      PTZ00169
      Location:5 → 293
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:204 → 296
      Mito_carr; Mitochondrial carrier protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z9M0 A1Z9M0
    Q7K2Y2 Q7K2Y2

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