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    CG4822 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33170, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4822provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031220
    Locus tag
    Dmel_CG4822
    See related
    AllianceGenome:FB:FBgn0031220
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    DmCG4822; Dmel\CG4822
    Summary
    Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult head. Orthologous to human ABCG1 (ATP binding cassette subfamily G member 1) and ABCG4 (ATP binding cassette subfamily G member 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4822 in Genome Data Viewer
    Location:
    21B2-21B2; 2-0.5 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (116970..121754, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (116970..121754, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene S-adenosylmethionine Synthetase Neighboring gene uncharacterized protein Neighboring gene NADH dehydrogenase (ubiquinone) 15 kDa subunit Neighboring gene antisense RNA:CR44969 Neighboring gene uncharacterized protein Neighboring gene Glutamine synthetase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mutants of the white ABCG Transporter in Drosophila melanogaster Have Deficient Olfactory Learning and Cholesterol Homeostasis. Myers JL, et al. Int J Mol Sci, 2021 Nov 30. PMID 34884779, Free PMC Article
    2. A global timing mechanism regulates cell-type-specific wiring programmes. Jain S, et al. Nature, 2022 Mar. PMID 35197627
    3. RNAi experiments in D. melanogaster: solutions to the overlooked problem of off-targets shared by independent dsRNAs. Seinen E, et al. PLoS One, 2010 Oct 1. PMID 20957038, Free PMC Article
    4. Characterization of a novel pesticide transporter and P-glycoprotein orthologues in Drosophila melanogaster. Denecke S, et al. Proc Biol Sci, 2022 May 25. PMID 35582794, Free PMC Article
    5. Vesicle-Mediated Steroid Hormone Secretion in Drosophila melanogaster. Yamanaka N, et al. Cell, 2015 Nov 5. PMID 26544939, Free PMC Article

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4822-PA
    CG4822-PB
    CG4822-PC
    CG4822-PD
    CG4822-PE
    CG4822-PF
    CG4822-PG
    CG4822-PH
    CG4822-PI
    NP_001033861.1
    NP_001033862.1
    NP_001033863.1
    NP_001033864.1
    NP_001259798.1
    NP_608493.2
    NP_722602.1
    NP_722603.1
    NP_722604.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      116970..121754 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001038772.2 → NP_001033861.1  uncharacterized protein Dmel_CG4822, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033861.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH11, Q9VPJ7
      Conserved Domains (3) summary
      cd03213
      Location:51 → 276
      ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
      TIGR00955
      Location:67 → 654
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
      pfam01061
      Location:381 → 587
      ABC2_membrane; ABC-2 type transporter

    2. NM_164363.2 → NP_722602.1  uncharacterized protein Dmel_CG4822, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722602.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH11, Q9VPJ7
      Related
      FBpp0077814
      Conserved Domains (3) summary
      cd03213
      Location:51 → 276
      ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
      TIGR00955
      Location:67 → 654
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
      pfam01061
      Location:381 → 587
      ABC2_membrane; ABC-2 type transporter

    3. NM_164364.3 → NP_722603.1  uncharacterized protein Dmel_CG4822, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722603.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH11, Q9VPJ7
      Related
      FBpp0077817
      Conserved Domains (3) summary
      cd03213
      Location:51 → 276
      ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
      TIGR00955
      Location:67 → 654
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
      pfam01061
      Location:381 → 587
      ABC2_membrane; ABC-2 type transporter

    4. NM_134649.4 → NP_608493.2  uncharacterized protein Dmel_CG4822, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608493.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH11, Q9VPJ7
      Related
      FBpp0077816, FBtr0078158
      Conserved Domains (3) summary
      cd03213
      Location:51 → 276
      ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
      TIGR00955
      Location:67 → 654
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
      pfam01061
      Location:381 → 587
      ABC2_membrane; ABC-2 type transporter

    5. NM_001272869.1 → NP_001259798.1  uncharacterized protein Dmel_CG4822, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259798.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PBY9
      Conserved Domains (1) summary
      cl21455
      Location:51 → 108
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    6. NM_001038774.2 → NP_001033863.1  uncharacterized protein Dmel_CG4822, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033863.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2PDV9
      Conserved Domains (1) summary
      cl21455
      Location:51 → 139
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    7. NM_164365.2 → NP_722604.1  uncharacterized protein Dmel_CG4822, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722604.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH11, Q9VPJ7
      Related
      FBpp0077815
      Conserved Domains (3) summary
      cd03213
      Location:51 → 276
      ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
      TIGR00955
      Location:67 → 654
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
      pfam01061
      Location:381 → 587
      ABC2_membrane; ABC-2 type transporter

    8. NM_001038773.2 → NP_001033862.1  uncharacterized protein Dmel_CG4822, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033862.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH11, Q9VPJ7
      Conserved Domains (3) summary
      cd03213
      Location:51 → 276
      ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
      TIGR00955
      Location:67 → 654
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
      pfam01061
      Location:381 → 587
      ABC2_membrane; ABC-2 type transporter

    9. NM_001038775.2 → NP_001033864.1  uncharacterized protein Dmel_CG4822, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033864.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2PDV8
      Conserved Domains (1) summary
      cl21455
      Location:51 → 108
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PBY9 M9PBY9
    Q2PDV8 Q2PDV8
    Q2PDV9 Q2PDV9
    Q8MQW6 Q8MQW6
    Q9VPJ7 Q9VPJ7

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