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    Gip GIP-like [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31960, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Gipprovided by FlyBase
    Official Full Name
    GIP-likeprovided by FlyBase
    Primary source
    FLYBASE:FBgn0011770
    Locus tag
    Dmel_CG2227
    See related
    AllianceGenome:FB:FBgn0011770
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG2227; Dmel\CG2227; gene C; GIP; T15
    Summary
    Predicted to enable hydroxypyruvate isomerase activity. Predicted to be involved in glyoxylate metabolic process. Located in extracellular region. Is expressed in adult head; embryonic/larval crystal cell; embryonic/larval midgut; and organism. Orthologous to human HYI (hydroxypyruvate isomerase (putative)). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Gip in Genome Data Viewer
    Location:
    9B7-9B7; 1-31 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10328877..10329872, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10222910..10223905, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene alpha-Mannosidase class I a Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Proper function of the Drosophila trp gene product during pupal development is important for normal visual transduction in the adult. Wong F, et al. Neuron, 1989 Jul. PMID 2482778
    2. Overlapping transcription units in the transient receptor potential locus of Drosophila melanogaster. Wong F, et al. Somat Cell Mol Genet, 1987 Nov. PMID 3118483
    3. Lola-I is a promoter pioneer factor that establishes de novo Pol II pausing during development. Ramalingam V, et al. Nat Commun, 2023 Sep 21. PMID 37735176, Free PMC Article
    4. Anti-ageing effects of red ginseng on female Drosophila melanogaster. Hou W, et al. J Cell Mol Med, 2020 Mar. PMID 32022406, Free PMC Article
    5. A proteomic approach for the analysis of instantly released wound and immune proteins in Drosophila melanogaster hemolymph. Vierstraete E, et al. Proc Natl Acad Sci U S A, 2004 Jan 13. PMID 14707262, Free PMC Article

    See all (46) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables hydroxypyruvate isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydroxypyruvate isomerase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glyoxylate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glyoxylate metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region HDA PubMed 

    General protein information

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    Preferred Names
    GIP-like
    Names
    CG2227-PA
    Gip-PA
    glyoxylate-induced protein
    hydroxypyruvate isomerase
    NP_511106.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      10328877..10329872 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078551.4 → NP_511106.1  GIP-like [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_511106.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P36951, Q9W2W4
      Related
      FBpp0071406
      Conserved Domains (2) summary
      TIGR03234
      Location:4 → 256
      OH-pyruv-isom; hydroxypyruvate isomerase
      pfam01261
      Location:24 → 222
      AP_endonuc_2; Xylose isomerase-like TIM barrel
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36951.1 P36951

    Gene LinkOut

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