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    CG3823 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31573, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3823provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029863
    Locus tag
    Dmel_CG3823
    See related
    AllianceGenome:FB:FBgn0029863
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3823
    Summary
    Predicted to enable phosphatidylinositol bisphosphate binding activity. Predicted to be involved in intermembrane lipid transfer. Predicted to be located in late endosome. Human ortholog(s) of this gene implicated in familial isolated deficiency of vitamin E. Orthologous to human TTPA (alpha tocopherol transfer protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3823 in Genome Data Viewer
    Location:
    5E7-5E8; 1-16 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (6303975..6306745)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (6198008..6200778)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Changes in Drosophila melanogaster midgut proteins in response to dietary Bowman-Birk inhibitor. Li HM, et al. Insect Mol Biol, 2007 Oct. PMID 17725801
    2. Profiling ATM regulated genes in Drosophila at physiological condition and after ionizing radiation. Liu J, et al. Hereditas, 2022 Oct 21. PMID 36271387, Free PMC Article
    3. Specific transcriptional responses to juvenile hormone and ecdysone in Drosophila. Beckstead RB, et al. Insect Biochem Mol Biol, 2007 Jun. PMID 17517334, Free PMC Article
    4. RNAseq analysis of the drug jian-yan-ling (JYL) using both in vivo and in vitro models. Zhang X, et al. Heliyon, 2023 May. PMID 37251843, Free PMC Article
    5. Two subunits specific to the PBAP chromatin remodeling complex have distinct and redundant functions during drosophila development. Carrera I, et al. Mol Cell Biol, 2008 Sep. PMID 18573871, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables phosphatidylinositol bisphosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatidylinositol bisphosphate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in intermembrane lipid transfer ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in late endosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3823-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      6303975..6306745
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132085.2 → NP_572313.1  uncharacterized protein Dmel_CG3823 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572313.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W408
      Related
      FBpp0070865
      Conserved Domains (1) summary
      cd00170
      Location:90 → 239
      SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W408 Q9W408

    Gene LinkOut

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