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    Cyp6t1 Cytochrome P450 6t1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33127, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cyp6t1provided by FlyBase
    Official Full Name
    Cytochrome P450 6t1provided by FlyBase
    Primary source
    FLYBASE:FBgn0031182
    Locus tag
    Dmel_CG1644
    See related
    AllianceGenome:FB:FBgn0031182
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    6t1; CG1644; Cyp6T1; Dmel\CG1644
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Predicted to be involved in insecticide catabolic process and response to DDT. Is expressed in adult head; embryonic/larval midgut; gonad; and organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cyp6t1 in Genome Data Viewer
    Location:
    20A1-20A1; 1-66 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (21517434..21519218, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (21388461..21390245, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45510 Neighboring gene long non-coding RNA:CR45511 Neighboring gene long non-coding RNA:CR45082 Neighboring gene long non-coding RNA:CR46472 Neighboring gene long non-coding RNA:CR44711

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene Regulatory Variation in Drosophila melanogaster Renal Tissue. Glaser-Schmitt A, et al. Genetics, 2018 Sep. PMID 29976765, Free PMC Article
    2. Independent effects of cis- and trans-regulatory variation on gene expression in Drosophila melanogaster. Wittkopp PJ, et al. Genetics, 2008 Mar. PMID 18245838, Free PMC Article
    3. Daedalus and Gasz recruit Armitage to mitochondria, bringing piRNA precursors to the biogenesis machinery. Munafò M, et al. Genes Dev, 2019 Jul 1. PMID 31123065, Free PMC Article
    4. High fat diet induces sex-specific differential gene expression in Drosophila melanogaster. Stobdan T, et al. PLoS One, 2019. PMID 30861021, Free PMC Article
    5. Evolutionary changes in cis and trans gene regulation. Wittkopp PJ, et al. Nature, 2004 Jul 1. PMID 15229602

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in insecticide catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in response to DDT IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450 6t1
    Names
    CG1644-PA
    Cyp6t1-PA
    cytochrome P450
    NP_608457.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      21517434..21519218 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134613.3 → NP_608457.1  cytochrome P450 6t1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608457.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VRI9
      Related
      FBpp0076908
      Conserved Domains (1) summary
      cl12078
      Location:91 → 515
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VRI9.1 Q9VRI9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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