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    Cda4 Chitin deacetylase-like 4 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33144, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cda4provided by FlyBase
    Official Full Name
    Chitin deacetylase-like 4provided by FlyBase
    Primary source
    FLYBASE:FBgn0052499
    Locus tag
    Dmel_CG32499
    See related
    AllianceGenome:FB:FBgn0052499
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE51076; CG12447; CG13238; CG32499; CG9557; CG9558; DmCDA4; Dmel\CG32499
    Summary
    Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Located in perivitelline space. Is expressed in several structures, including adult brain cell body rind; embryonic dorsal epidermis; embryonic head epidermis; embryonic/larval tracheal section; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cda4 in Genome Data Viewer
    Location:
    20C3-20D1; 1-66 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (22583634..22632710, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (21985470..22034546, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Clusterin associated protein 1 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44997 Neighboring gene long non-coding RNA:CR44109 Neighboring gene long non-coding RNA:CR45464

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Domain organization and phylogenetic analysis of proteins from the chitin deacetylase gene family of Tribolium castaneum and three other species of insects. Dixit R, et al. Insect Biochem Mol Biol, 2008 Apr. PMID 18342249
    2. Identification of cis-regulatory modules encoding temporal dynamics during development. Potier D, et al. BMC Genomics, 2014 Jun 27. PMID 24972496, Free PMC Article
    3. Acute manipulation and real-time visualization of membrane trafficking and exocytosis in Drosophila. Glashauser J, et al. Dev Cell, 2023 Apr 24. PMID 37023749
    4. Tramtrack is genetically upstream of genes controlling tracheal tube size in Drosophila. Rotstein B, et al. PLoS One, 2011. PMID 22216153, Free PMC Article
    5. Identification of FGF-dependent genes in the Drosophila tracheal system. Stahl M, et al. Gene Expr Patterns, 2007 Jan. PMID 16949886

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: c22586349-22586164 mobile_element_type = transposon:INE-1{}3108
    • Loc: c22588252-22588170 mobile_element_type = transposon:INE-1{}3109
    • Loc: c22592613-22592167 mobile_element_type = transposon:INE-1{}3110
    • Loc: c22596811-22596387 mobile_element_type = transposon:INE-1{}3128
    • Loc: c22600216-22599973 mobile_element_type = transposon:INE-1{}3129
    • Loc: c22617609-22617436 mobile_element_type = transposon:INE-1{}3131

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables chitin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    NOT enables chitin deacetylase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in perivitelline space HDA PubMed 

    General protein information

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    Preferred Names
    chitin deacetylase-like 4
    Names
    CG32499-PA
    Cda4-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      22583634..22632710 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167788.2 → NP_728468.1  chitin deacetylase-like 4 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728468.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VR69
      Related
      FBpp0077054
      Conserved Domains (2) summary
      cd10974
      Location:130 → 396
      CE4_CDA_like_1; Putative catalytic domain of chitin deacetylase-like proteins with additional chitin-binding peritrophin-A domain (ChBD) and/or a low-density lipoprotein receptor class A domain (LDLa)
      pfam01607
      Location:33 → 80
      CBM_14; Chitin binding Peritrophin-A domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VR69 Q9VR69

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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