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    Cda5 Chitin deacetylase-like 5 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33158, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cda5provided by FlyBase
    Official Full Name
    Chitin deacetylase-like 5provided by FlyBase
    Primary source
    FLYBASE:FBgn0051973
    Locus tag
    Dmel_CG31973
    See related
    AllianceGenome:FB:FBgn0051973
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RH43162; CG2761; CG2776; CG31973; DmCDA5; Dmel\CG31973
    Summary
    Predicted to enable chitin deacetylase activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in extracellular region. Is expressed in several structures, including embryonic epipharynx; embryonic head epidermis; embryonic hypopharynx; epidermis; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cda5 in Genome Data Viewer
    Location:
    21B1-21B1; 2-0.5 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (25402..65404, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (25402..65404, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene lethal (2) giant larvae Neighboring gene antisense RNA:CR43609 Neighboring gene Ionotropic receptor 21a Neighboring gene long non-coding RNA:CR46254 Neighboring gene long non-coding RNA:CR45339 Neighboring gene long non-coding RNA:CR45340 Neighboring gene debra

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Domain organization and phylogenetic analysis of proteins from the chitin deacetylase gene family of Tribolium castaneum and three other species of insects. Dixit R, et al. Insect Biochem Mol Biol, 2008 Apr. PMID 18342249
    2. The Ionotropic Receptors IR21a and IR25a mediate cool sensing in Drosophila. Ni L, et al. Elife, 2016 Apr 29. PMID 27126188, Free PMC Article
    3. Abnormalities in cell proliferation and apico-basal cell polarity are separable in Drosophila lgl mutant clones in the developing eye. Grzeschik NA, et al. Dev Biol, 2007 Nov 1. PMID 17870065, Free PMC Article
    4. Transposable element dynamics and PIWI regulation impacts lncRNA and gene expression diversity in Drosophila ovarian cell cultures. Sytnikova YA, et al. Genome Res, 2014 Dec. PMID 25267525, Free PMC Article
    5. Conditional switches for extracellular matrix patterning in Drosophila melanogaster. Khokhar A, et al. Genetics, 2008 Mar. PMID 18245854, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: c27788-27530 mobile_element_type = transposon:INE-1{}1753

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables chitin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables chitin deacetylase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    chitin deacetylase-like 5
    Names
    CG31973-PA
    CG31973-PB
    CG31973-PE
    CG31973-PF
    CG31973-PG
    CG31973-PH
    CG31973-PI
    CG31973-PJ
    Cda5-PA
    Cda5-PB
    Cda5-PE
    Cda5-PF
    Cda5-PG
    Cda5-PH
    Cda5-PI
    Cda5-PJ
    NP_001097044.2
    NP_001097045.1
    NP_001245805.1
    NP_001245806.1
    NP_001245807.1
    NP_001245808.1
    NP_722589.1
    NP_722590.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      25402..65404 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001258877.2 → NP_001245806.1  chitin deacetylase-like 5, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245806.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NCL3
      Conserved Domains (2) summary
      cd10975
      Location:1456 → 1718
      CE4_CDA_like_2; Putative catalytic domain of chitin deacetylase-like proteins
      pfam01607
      Location:58 → 106
      CBM_14; Chitin binding Peritrophin-A domain

    2. NM_001103575.2 → NP_001097045.1  chitin deacetylase-like 5, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097045.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8V4
      Conserved Domains (2) summary
      cd10975
      Location:705 → 968
      CE4_CDA_like_2; Putative catalytic domain of chitin deacetylase-like proteins
      pfam01607
      Location:58 → 106
      CBM_14; Chitin binding Peritrophin-A domain

    3. NM_164353.2 → NP_722589.1  chitin deacetylase-like 5, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722589.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VPI4
      Related
      FBpp0077821
      Conserved Domains (2) summary
      cd10975
      Location:705 → 967
      CE4_CDA_like_2; Putative catalytic domain of chitin deacetylase-like proteins
      pfam01607
      Location:58 → 106
      CBM_14; Chitin binding Peritrophin-A domain

    4. NM_164354.3 → NP_722590.2  chitin deacetylase-like 5, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722590.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VPI3
      Conserved Domains (2) summary
      cd10975
      Location:1664 → 1926
      CE4_CDA_like_2; Putative catalytic domain of chitin deacetylase-like proteins
      pfam01607
      Location:58 → 106
      CBM_14; Chitin binding Peritrophin-A domain

    5. NM_001258878.2 → NP_001245807.1  chitin deacetylase-like 5, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245807.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NE36
      Conserved Domains (2) summary
      cd10975
      Location:557 → 819
      CE4_CDA_like_2; Putative catalytic domain of chitin deacetylase-like proteins
      pfam01607
      Location:58 → 106
      CBM_14; Chitin binding Peritrophin-A domain

    6. NM_001103574.3 → NP_001097044.2  chitin deacetylase-like 5, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097044.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8DYS5
      Conserved Domains (2) summary
      cd10975
      Location:1556 → 1818
      CE4_CDA_like_2; Putative catalytic domain of chitin deacetylase-like proteins
      pfam01607
      Location:58 → 106
      CBM_14; Chitin binding Peritrophin-A domain

    7. NM_001258879.2 → NP_001245808.1  chitin deacetylase-like 5, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245808.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NCX5
      Conserved Domains (2) summary
      cd10975
      Location:1516 → 1778
      CE4_CDA_like_2; Putative catalytic domain of chitin deacetylase-like proteins
      pfam01607
      Location:58 → 106
      CBM_14; Chitin binding Peritrophin-A domain

    8. NM_001258876.2 → NP_001245805.1  chitin deacetylase-like 5, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245805.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NEJ4
      Conserved Domains (2) summary
      cd10975
      Location:1228 → 1490
      CE4_CDA_like_2; Putative catalytic domain of chitin deacetylase-like proteins
      pfam01607
      Location:58 → 106
      CBM_14; Chitin binding Peritrophin-A domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8DYS5 A8DYS5
    M9NCL3 M9NCL3
    M9NCX5 M9NCX5
    M9NE36 M9NE36
    M9NEJ4 M9NEJ4
    Q0E8V4 Q0E8V4
    Q8MQI4 Q8MQI4
    Q9VPI3 Q9VPI3
    Q9VPI4 Q9VPI4

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