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    CG3008 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33693, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3008provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031643
    Locus tag
    Dmel_CG3008
    See related
    AllianceGenome:FB:FBgn0031643
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3008
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in cytoplasm and nucleus. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in cytosol. Is expressed in several structures, including anterior endoderm; embryonic/larval midgut primordium; ganglia; germline cell; and mesoderm. Orthologous to human RIOK3 (RIO kinase 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3008 in Genome Data Viewer
    Location:
    25B1-25B1; 2-14 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4883298..4885669)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4883298..4885669)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene smog Neighboring gene Chorion factor 2 Neighboring gene uncharacterized protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Piwi interacts with chromatin at nuclear pores and promiscuously binds nuclear transcripts in Drosophila ovarian somatic cells. Ilyin AA, et al. Nucleic Acids Res, 2017 Jul 27. PMID 28472469, Free PMC Article
    2. Classification and functional annotation of eukaryotic protein kinases. Miranda-Saavedra D, et al. Proteins, 2007 Sep 1. PMID 17557329
    3. Quantitative proteomic analysis of protein complexes: concurrent identification of interactors and their state of phosphorylation. Pflieger D, et al. Mol Cell Proteomics, 2008 Feb. PMID 17956857
    4. New comparative genomics approach reveals a conserved health span signature across species. Antosh M, et al. Aging (Albany NY), 2011 Jun. PMID 21775776, Free PMC Article
    5. The Spalt Transcription Factors Generate the Transcriptional Landscape of the Drosophila melanogaster Wing Pouch Central Region. Organista MF, et al. PLoS Genet, 2015 Aug. PMID 26241320, Free PMC Article

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of preribosome, small subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3008-PA
    NP_608871.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      4883298..4885669
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135027.4 → NP_608871.1  uncharacterized protein Dmel_CG3008 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608871.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VR42
      Related
      FBpp0077081
      Conserved Domains (2) summary
      COG1718
      Location:242 → 505
      RIO1; Serine/threonine-protein kinase RIO1 [Signal transduction mechanisms]
      cd05146
      Location:278 → 488
      RIO3_euk; Catalytic domain of the atypical protein serine kinase, RIO3 kinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VR42 Q9VR42

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