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    CG7881 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35521, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7881provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033048
    Locus tag
    Dmel_CG7881
    See related
    AllianceGenome:FB:FBgn0033048
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7881
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic anion transport. Predicted to be active in membrane. Is expressed in adult head; embryonic midgut chamber; embryonic/larval hindgut; embryonic/larval midgut; and embryonic/larval salivary gland. Human ortholog(s) of this gene implicated in gout. Orthologous to human SLC17A1 (solute carrier family 17 member 1); SLC17A3 (solute carrier family 17 member 3); and SLC17A4 (solute carrier family 17 member 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7881 in Genome Data Viewer
    Location:
    42A4-42A4; 2-55 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (5960275..5966856, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (1847780..1854361, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44126 Neighboring gene antisense RNA:CR46269 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44127 Neighboring gene Bub1-related kinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Embryonic expression patterns of Drosophila ACS family genes related to the human sialin gene. Laridon B, et al. Gene Expr Patterns, 2008 Apr. PMID 18255354
    2. Roles of major facilitator superfamily transporters in phosphate response in Drosophila. Bergwitz C, et al. PLoS One, 2012. PMID 22359624, Free PMC Article
    3. Functional antagonism between histone H3K4 demethylases in vivo. Di Stefano L, et al. Genes Dev, 2011 Jan 1. PMID 21205864, Free PMC Article
    4. Age-specific variation in immune response in Drosophila melanogaster has a genetic basis. Felix TM, et al. Genetics, 2012 Jul. PMID 22554890, Free PMC Article
    5. A phylogenetic analysis between humans and D. melanogaster: A repertoire of solute carriers in humans and flies. Ceder MM, et al. Gene, 2022 Jan 30. PMID 34673204

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7881-PA
    CG7881-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      5960275..5966856 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299215.1 → NP_001286144.1  uncharacterized protein Dmel_CG7881, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286144.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MS84
      Conserved Domains (2) summary
      cd06174
      Location:18 → 437
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00894
      Location:12 → 449
      2A0114euk; Na(+)-dependent inorganic phosphate cotransporter

    2. NM_136346.2 → NP_610190.2  uncharacterized protein Dmel_CG7881, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610190.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MS84
      Related
      FBpp0085369
      Conserved Domains (2) summary
      cd06174
      Location:18 → 437
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00894
      Location:12 → 449
      2A0114euk; Na(+)-dependent inorganic phosphate cotransporter
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MS84 Q8MS84

    Gene LinkOut

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