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    Marc Mitochondrial amidoxime reducing component [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36014, updated on 9-Dec-2024

    Summary

    Official Symbol
    Marcprovided by FlyBase
    Official Full Name
    Mitochondrial amidoxime reducing componentprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033451
    Locus tag
    Dmel_CG1665
    See related
    AllianceGenome:FB:FBgn0033451
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1665; Dmel\CG1665; IP19920p; mArc
    Summary
    Predicted to enable nitrite reductase activity. Predicted to contribute to nitrite reductase (NO-forming) activity. Predicted to be involved in cellular detoxification of nitrogen compound and nitric oxide biosynthetic process. Predicted to be located in mitochondrion. Predicted to be part of nitric-oxide synthase complex. Is expressed in adult head; adult heart; and organism. Orthologous to human MTARC1 (mitochondrial amidoxime reducing component 1) and MTARC2 (mitochondrial amidoxime reducing component 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Marc in Genome Data Viewer
    Location:
    46B4-46B4; 2-61 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (9839776..9841163)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5727281..5728668)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene hebe Neighboring gene uncharacterized protein Neighboring gene Lsm11 Neighboring gene Vesicle-associated membrane protein 7 Neighboring gene sting Neighboring gene Proteasome alpha7 subunit Neighboring gene Origin recognition complex subunit 6

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables molybdenum ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to nitrite reductase (NO-forming) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables nitrite reductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables oxidoreductase activity, acting on other nitrogenous compounds as donors ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cellular detoxification of nitrogen compound ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in nitric oxide biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of nitric-oxide synthase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    mitochondrial amidoxime reducing component
    Names
    CG1665-PA
    Marc-PA
    NP_610523.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      9839776..9841163
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136679.5NP_610523.2  mitochondrial amidoxime reducing component [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610523.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z803, Q8SXE5
      Related
      FBpp0087562
      Conserved Domains (3) summary
      COG3217
      Location:52337
      YcbX; Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains [General function prediction only]
      pfam03473
      Location:219336
      MOSC; MOSC domain
      pfam03476
      Location:50172
      MOSC_N; MOSC N-terminal beta barrel domain