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    CG6262 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36833, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6262provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034121
    Locus tag
    Dmel_CG6262
    See related
    AllianceGenome:FB:FBgn0034121
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6262
    Summary
    Predicted to enable alpha,alpha-trehalase activity. Predicted to be involved in trehalose catabolic process. Is expressed in adult head and spermatozoon. Orthologous to human TREH (trehalase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6262 in Genome Data Viewer
    Location:
    53C2-53C2; 2-80 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (16359730..16363524)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (12247235..12251029)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43416 Neighboring gene long non-coding RNA:CR45322 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45316 Neighboring gene long non-coding RNA:CR45317

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular characterization of Tps1 and Treh genes in Drosophila and their role in body water homeostasis. Yoshida M, et al. Sci Rep, 2016 Jul 29. PMID 27469628, Free PMC Article
    2. Metabolomics provide new insights into mechanisms of Wolbachia-induced paternal defects in Drosophila melanogaster. Zhang HB, et al. PLoS Pathog, 2021 Aug. PMID 34383852, Free PMC Article
    3. Quantitative Proteomic Analyses of Molecular Mechanisms Associated with Cytoplasmic Incompatibility in Drosophila melanogaster Induced by Wolbachia. Yuan LL, et al. J Proteome Res, 2015 Sep 4. PMID 26220534
    4. Lack of global meiotic sex chromosome inactivation, and paucity of tissue-specific gene expression on the Drosophila X chromosome. Mikhaylova LM, et al. BMC Biol, 2011 May 4. PMID 21542906, Free PMC Article
    5. Glial Glycolysis Is Essential for Neuronal Survival in Drosophila. Volkenhoff A, et al. Cell Metab, 2015 Sep 1. PMID 26235423

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables alpha,alpha-trehalase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables alpha,alpha-trehalase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in trehalose catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in trehalose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6262-PA
    CG6262-PB
    CG6262-PC
    NP_611123.2
    NP_725574.2
    NP_725575.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      16359730..16363524
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166172.3 → NP_725574.2  uncharacterized protein Dmel_CG6262, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725574.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZAF2, Q6NN99
      Related
      FBpp0086295
      Conserved Domains (1) summary
      cl17346
      Location:1 → 365
      Trehalase; Trehalase

    2. NM_137279.3 → NP_611123.2  uncharacterized protein Dmel_CG6262, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611123.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZAE9, Q7YTX8
      Related
      FBpp0086296
      Conserved Domains (1) summary
      cl17346
      Location:33 → 540
      Trehalase; Trehalase

    3. NM_166173.2 → NP_725575.1  uncharacterized protein Dmel_CG6262, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725575.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZAF3, Q8IHG4
      Related
      FBpp0086297
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZAE9 A1ZAE9
    A1ZAF2 A1ZAF2
    A1ZAF3 A1ZAF3
    Q7YTX8 Q7YTX8
    Q8IHG4 Q8IHG4

    Gene LinkOut

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