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    Art7 Arginine methyltransferase 7 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37664, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Art7provided by FlyBase
    Official Full Name
    Arginine methyltransferase 7provided by FlyBase
    Primary source
    FLYBASE:FBgn0034817
    Locus tag
    Dmel_CG9882
    See related
    AllianceGenome:FB:FBgn0034817
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9882; dart7; DART7; Dmel\CG9882; PRMT7
    Summary
    Enables protein-arginine omega-N symmetric methyltransferase activity. Involved in peptidyl-arginine methylation. Is expressed in ovary. Orthologous to human PRMT7 (protein arginine methyltransferase 7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Art7 in Genome Data Viewer
    Location:
    59C3-59C3; 2-102 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23076688..23079038, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18964211..18966561, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene transfer RNA:Serine-TGA 2-1 Neighboring gene Fibrillarin Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Gustatory receptor 59a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The lncRNA hsrω regulates arginine dimethylation of human FUS to cause its proteasomal degradation in Drosophila. Lo Piccolo L, et al. J Cell Sci, 2019 Oct 23. PMID 31519807, Free PMC Article
    2. A novel BLAST-Based Relative Distance (BBRD) method can effectively group members of protein arginine methyltransferases and suggest their evolutionary relationship. Wang YC, et al. Mol Phylogenet Evol, 2015 Mar. PMID 25576770
    3. Evolutionarily conserved protein arginine methyltransferases in non-mammalian animal systems. Wang YC, et al. FEBS J, 2012 Mar. PMID 22251447
    4. Neurodevelopmental disorders with epigenetic dysregulation and Drosophila. Sang Cho K, et al. Front Biosci (Landmark Ed), 2019 Jun 1. PMID 31136982
    5. Helena and BS: Two Travellers between the Genera Drosophila and Zaprionus. Simão MC, et al. Genome Biol Evol, 2018 Oct 1. PMID 30165545, Free PMC Article

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables histone methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-arginine N-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-arginine N-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-arginine N-methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein-arginine omega-N symmetric methyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin remodeling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in peptidyl-arginine methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in peptidyl-arginine methylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    arginine methyltransferase 7
    Names
    Art7-PB
    CG9882-PB
    NP_611753.4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23076688..23079038 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137909.5 → NP_611753.4  arginine methyltransferase 7 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611753.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B5X512, Q8MYV1, Q9W1V1
      Conserved Domains (1) summary
      cl17173
      Location:36 → 186
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W1V1.4 Q9W1V1

    Gene LinkOut

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