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    Ir60e Ionotropic receptor 60e [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37917, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ir60eprovided by FlyBase
    Official Full Name
    Ionotropic receptor 60eprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035019
    Locus tag
    Dmel_CG13592
    See related
    AllianceGenome:FB:FBgn0035019
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    60e; CG13592; DmelIR60e; Dmel\CG13592; IR60e
    Summary
    Predicted to enable ligand-gated monoatomic ion channel activity. Predicted to be involved in detection of chemical stimulus. Predicted to be located in membrane. Is expressed in larval gustatory receptor neuron of the dorsal pharyngeal sense organ. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ir60e in Genome Data Viewer
    Location:
    60D4-60D4; 2-107 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24529554..24531272, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20417077..20418795, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Ionotropic receptor 60f Neighboring gene uncharacterized protein Neighboring gene BRCA2, DNA repair associated Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Candidate ionotropic taste receptors in the Drosophila larva. Stewart S, et al. Proc Natl Acad Sci U S A, 2015 Apr 7. PMID 25825777, Free PMC Article
    2. The Drosophila IR20a clade of ionotropic receptors are candidate taste and pheromone receptors. Koh TW, et al. Neuron, 2014 Aug 20. PMID 25123314, Free PMC Article
    3. The multidimensional ionotropic receptors of Drosophila melanogaster. Rimal S, et al. Insect Mol Biol, 2018 Feb. PMID 28857341
    4. A Molecular and Cellular Context-Dependent Role for Ir76b in Detection of Amino Acid Taste. Ganguly A, et al. Cell Rep, 2017 Jan 17. PMID 28099851, Free PMC Article
    5. An expression atlas of variant ionotropic glutamate receptors identifies a molecular basis of carbonation sensing. Sánchez-Alcañiz JA, et al. Nat Commun, 2018 Oct 12. PMID 30315166, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ionotropic receptor 60e
    Names
    CG13592-PD
    Ir60e-PD
    NP_611927.3
    • point mutation, may be evolving pseudogene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24529554..24531272 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138083.3 → NP_611927.3  ionotropic receptor 60e [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611927.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W155
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W155 Q9W155

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