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    CG32305 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 317967, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG32305provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052305
    Locus tag
    Dmel_CG32305
    See related
    AllianceGenome:FB:FBgn0052305
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    AC; CG8970; Dmel\CG32305
    Summary
    Predicted to enable adenylate cyclase activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and cAMP biosynthetic process. Predicted to be active in plasma membrane. Orthologous to human ADCY2 (adenylate cyclase 2) and ADCY7 (adenylate cyclase 7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG32305 in Genome Data Viewer
    Location:
    62D4-62D4; 3-2 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (2248635..2252729)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (2248635..2252729)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Adenylyl cyclase X D Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Elongator complex protein 5 Neighboring gene peptide O-xylosyltransferase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Adenylyl cyclase encoded by AC78C participates in sugar perception in Drosophila melanogaster. Ueno K, et al. Eur J Neurosci, 2008 Nov. PMID 19046378
    2. E and M circadian pacemaker neurons use different PDF receptor signalosome components in drosophila. Duvall LB, et al. J Biol Rhythms, 2013 Aug. PMID 23929551, Free PMC Article
    3. The circadian neuropeptide PDF signals preferentially through a specific adenylate cyclase isoform AC3 in M pacemakers of Drosophila. Duvall LB, et al. PLoS Biol, 2012. PMID 22679392, Free PMC Article
    4. Innate and learned odor-guided behaviors utilize distinct molecular signaling pathways in a shared dopaminergic circuit. Noyes NC, et al. Cell Rep, 2023 Feb 28. PMID 36701232, Free PMC Article
    5. Fatty acid tryptamide from cacao elongates Drosophila melanogaster lifespan with sirtuin-dependent heat shock protein expression. Kanno K, et al. Sci Rep, 2022 Jul 15. PMID 35840713, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables adenylate cyclase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphorus-oxygen lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cyclic nucleotide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32305-PB
    NP_728725.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      2248635..2252729
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167940.2 → NP_728725.2  uncharacterized protein Dmel_CG32305 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728725.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IRF5
      Conserved Domains (2) summary
      smart00044
      Location:251 → 449
      CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
      cl11967
      Location:292 → 445
      Nucleotidyl_cyc_III; Class III nucleotidyl cyclases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IRF5 Q8IRF5

    Gene LinkOut

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