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    CG6813 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41396, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6813provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037923
    Locus tag
    Dmel_CG6813
    See related
    AllianceGenome:FB:FBgn0037923
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG31372; Dmel\CG6813
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6813 in Genome Data Viewer
    Location:
    86E13-86E13; 3-51 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11625051..11626638, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7450773..7452360, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ZAD and Architectural Function 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Jupiter, a new Drosophila protein associated with microtubules. Karpova N, et al. Cell Motil Cytoskeleton, 2006 May. PMID 16518797
    2. Twenty-seven ZAD-ZNF genes of Drosophila melanogaster are orthologous to the embryo polarity determining mosquito gene cucoid. Li M, et al. PLoS One, 2023. PMID 36595500, Free PMC Article
    3. ZAD-Domain Is Essential for Nuclear Localization of Insulator Proteins in Drosophila melanogaster. Zolotarev NA, et al. Acta Naturae, 2016 Jul-Sep. PMID 27795848, Free PMC Article
    4. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila. Kasinathan B, et al. Elife, 2020 Nov 10. PMID 33169670, Free PMC Article
    5. The genetic basis for variation in resistance to infection in the Drosophila melanogaster genetic reference panel. Wang JB, et al. PLoS Pathog, 2017 Mar. PMID 28257468, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription cis-regulatory region binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6813-PB
    CG6813-PC
    CG6813-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      11625051..11626638 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300361.1 → NP_001287290.1  uncharacterized protein Dmel_CG6813, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287290.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3DMZ5, Q9VGL1
      Conserved Domains (3) summary
      sd00017
      Location:144 → 164
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:6 → 76
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam13465
      Location:186 → 211
      zf-H2C2_2; Zinc-finger double domain

    2. NM_169413.2 → NP_731605.2  uncharacterized protein Dmel_CG6813, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731605.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3DMZ5, Q9VGL1
      Conserved Domains (3) summary
      sd00017
      Location:144 → 164
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:6 → 76
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam13465
      Location:186 → 211
      zf-H2C2_2; Zinc-finger double domain

    3. NM_001170119.1 → NP_001163590.1  uncharacterized protein Dmel_CG6813, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163590.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JII8
      Conserved Domains (4) summary
      COG5112
      Location:256 → 294
      UFD2; U1-like Zn-finger-containing protein [General function prediction only]
      sd00017
      Location:144 → 164
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:6 → 76
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam13465
      Location:186 → 211
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E1JII8 E1JII8
    Q9VGL1 Q9VGL1

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