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    Ugt37A3 UDP-glycosyltransferase family 37 member A3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41574, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ugt37A3provided by FlyBase
    Official Full Name
    UDP-glycosyltransferase family 37 member A3provided by FlyBase
    Primary source
    FLYBASE:FBgn0038083
    Locus tag
    Dmel_CG5999
    See related
    AllianceGenome:FB:FBgn0038083
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG5999; Dmel\CG5999; UGT37A3
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in several diseases, including alcoholic pancreatitis; bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; and female reproductive organ cancer (multiple). Orthologous to several human genes including UGT1A1 (UDP glucuronosyltransferase family 1 member A1); UGT1A10 (UDP glucuronosyltransferase family 1 member A10); and UGT1A3 (UDP glucuronosyltransferase family 1 member A3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ugt37A3 in Genome Data Viewer
    Location:
    87C8-87C8; 3-52 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12741958..12743680, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8567680..8569402, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44231 Neighboring gene long non-coding RNA:CR46238 Neighboring gene UDP-glycosyltransferase family 37 member A2 Neighboring gene beaten path Vc Neighboring gene long non-coding RNA:CR44233

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Effects of lithium chloride on the gene expression profiles in Drosophila heads. Kasuya J, et al. Neurosci Res, 2009 Aug. PMID 19410610, Free PMC Article
    2. Pb exposure causes non-linear accumulation of Pb in D. melanogaster controlled by metallothionein B and exerts ecological effects. Yu X, et al. Sci Total Environ, 2023 Nov 20. PMID 37499811
    3. Genome-wide transcription analysis of clinal genetic variation in Drosophila. Chen Y, et al. PLoS One, 2012. PMID 22514645, Free PMC Article
    4. The requirement of IRE1 and XBP1 in resolving physiological stress during Drosophila development. Huang HW, et al. J Cell Sci, 2017 Sep 15. PMID 28775151, Free PMC Article
    5. Experimentally induced active and quiet sleep engage non-overlapping transcriptional programs in Drosophila. Anthoney N, et al. Elife, 2023 Nov 1. PMID 37910019, Free PMC Article

    See all (47) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables UDP-glycosyltransferase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycosylation ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    UDP-glycosyltransferase family 37 member A3
    Names
    CG5999-PB
    Ugt37A3-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      12741958..12743680 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141972.2 → NP_650229.2  UDP-glycosyltransferase family 37 member A3 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650229.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      C0P8M3, Q9VG29
      Conserved Domains (2) summary
      PHA03392
      Location:1 → 490
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:37 → 526
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VG29 Q9VG29

    Gene LinkOut

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