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    EPB42 erythrocyte membrane protein band 4.2 [ Bos taurus (domestic cattle) ]

    Gene ID: 281754, updated on 27-Dec-2024

    Summary

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    Official Symbol
    EPB42provided by VGNC
    Official Full Name
    erythrocyte membrane protein band 4.2provided by VGNC
    Primary source
    VGNC:VGNC:28526
    See related
    Ensembl:ENSBTAG00000011439
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See EPB42 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (38405138..38424273, complement)

    Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 62 Neighboring gene cyclin D1 binding protein 1 Neighboring gene transfer RNA arginine (anticodon CCU) Neighboring gene multiple coagulation factor deficiency protein 2 homolog

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Molecular basis of bovine red-cell protein 4.2 polymorphism in Japanese black cattle. Matsumoto M, et al. Biochem J, 1998 May 15. PMID 9576866, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein-glutamine gamma-glutamyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in peptide cross-linking IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein 4.2
    Names
    P4.2
    erythrocyte protein 4.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174312.2 → NP_776737.1  protein 4.2

      See identical proteins and their annotated locations for NP_776737.1

      Status: PROVISIONAL

      Source sequence(s)
      AF030029
      UniProtKB/Swiss-Prot
      O46509, O46510
      UniProtKB/TrEMBL
      B0JYP3
      Related
      ENSBTAP00000035838.5, ENSBTAT00000035972.6
      Conserved Domains (3) summary
      smart00460
      Location:260 → 351
      TGc; Transglutaminase/protease-like homologues
      pfam00868
      Location:7 → 123
      Transglut_N; Transglutaminase family
      pfam00927
      Location:584 → 682
      Transglut_C; Transglutaminase family, C-terminal ig like domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      38405138..38424273 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O46510.3 GenPept UniProtKB/Swiss-Prot:O46510

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials