U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ROBO2 roundabout guidance receptor 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 534842, updated on 29-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    ROBO2provided by VGNC
    Official Full Name
    roundabout guidance receptor 2provided by VGNC
    Primary source
    VGNC:VGNC:34079
    See related
    BGD:BT12390; Ensembl:ENSBTAG00000010462
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ROBO2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 1 NC_037328.1 (24413044..25069185)

    Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene ferritin light chain Neighboring gene lipase I Neighboring gene uncharacterized LOC112448273 Neighboring gene uncharacterized LOC132345459 Neighboring gene bcl-2 homologous antagonist/killer-like Neighboring gene uncharacterized LOC112448343

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    roundabout homolog 2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037328.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      24413044..25069185
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024993901.2 → XP_024849669.1  roundabout homolog 2 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TNH6, F1N199
      Conserved Domains (5) summary
      cd05726
      Location:332 → 421
      Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
      cd07693
      Location:30 → 129
      Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
      smart00410
      Location:428 → 509
      IG_like; Immunoglobulin like
      cd00063
      Location:526 → 619
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl11960
      Location:137 → 221
      Ig; Immunoglobulin domain

    2. XM_024993905.2 → XP_024849673.1  roundabout homolog 2 isoform X2

      UniProtKB/TrEMBL
      F1N199
      Related
      ENSBTAP00070001404.1, ENSBTAT00070002468.1
      Conserved Domains (5) summary
      cd05726
      Location:332 → 421
      Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
      cd07693
      Location:30 → 129
      Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
      smart00410
      Location:428 → 509
      IG_like; Immunoglobulin like
      cd00063
      Location:526 → 619
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl11960
      Location:137 → 221
      Ig; Immunoglobulin domain

    3. XM_024993910.2 → XP_024849678.1  roundabout homolog 2 isoform X6

      UniProtKB/TrEMBL
      A0A3Q1MJK7, A0A3Q1N560
      Related
      ENSBTAP00070001414.1, ENSBTAT00070002478.1
      Conserved Domains (6) summary
      cd05726
      Location:332 → 421
      Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
      cd07693
      Location:30 → 129
      Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
      smart00410
      Location:428 → 509
      IG_like; Immunoglobulin like
      cd00063
      Location:526 → 619
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam16599
      Location:1309 → 1387
      PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
      cl11960
      Location:137 → 221
      Ig; Immunoglobulin domain

    4. XM_024993907.2 → XP_024849675.1  roundabout homolog 2 isoform X4

      UniProtKB/TrEMBL
      A0AAA9RV33, A0AAA9S6F8
      Related
      ENSBTAP00070001410.1, ENSBTAT00070002474.1
      Conserved Domains (5) summary
      cd05726
      Location:332 → 421
      Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
      cd07693
      Location:30 → 129
      Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
      smart00410
      Location:428 → 509
      IG_like; Immunoglobulin like
      cd00063
      Location:526 → 619
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl11960
      Location:137 → 221
      Ig; Immunoglobulin domain

    5. XM_024993915.2 → XP_024849683.1  roundabout homolog 2 isoform X8

      UniProtKB/TrEMBL
      A0A3Q1MJK7
      Conserved Domains (5) summary
      cd05726
      Location:332 → 421
      Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
      cd07693
      Location:30 → 129
      Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
      smart00410
      Location:428 → 509
      IG_like; Immunoglobulin like
      cd00063
      Location:526 → 619
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl11960
      Location:137 → 221
      Ig; Immunoglobulin domain

    6. XM_024993918.2 → XP_024849686.1  roundabout homolog 2 isoform X9

      UniProtKB/TrEMBL
      A0A3Q1MJK7
      Related
      ENSBTAP00070001422.1, ENSBTAT00070002486.1
      Conserved Domains (5) summary
      cd05726
      Location:332 → 421
      Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
      cd07693
      Location:30 → 129
      Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
      smart00409
      Location:428 → 509
      IG; Immunoglobulin
      cd00063
      Location:526 → 619
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl11960
      Location:137 → 221
      Ig; Immunoglobulin domain

    7. XM_059887558.1 → XP_059743541.1  roundabout homolog 2 isoform X3

      UniProtKB/TrEMBL
      A0AAA9RYB3, F1N199
      Related
      ENSBTAP00070001406.1, ENSBTAT00070002470.1

    8. XM_059887563.1 → XP_059743546.1  roundabout homolog 2 isoform X5

      UniProtKB/TrEMBL
      A0AAA9RV33

    9. XM_059887572.1 → XP_059743555.1  roundabout homolog 2 isoform X10

      UniProtKB/TrEMBL
      A0A3Q1MJK7

    10. XM_024993922.2 → XP_024849690.1  roundabout homolog 2 isoform X11

      UniProtKB/TrEMBL
      A0A3Q1MJK7, A0AAA9S7H1
      Related
      ENSBTAP00070001398.1, ENSBTAT00070002462.1
      Conserved Domains (5) summary
      cd05726
      Location:332 → 421
      Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
      cd07693
      Location:30 → 129
      Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
      smart00410
      Location:428 → 509
      IG_like; Immunoglobulin like
      cd00063
      Location:526 → 619
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl11960
      Location:137 → 221
      Ig; Immunoglobulin domain

    11. XM_059887566.1 → XP_059743549.1  roundabout homolog 2 isoform X7

      UniProtKB/TrEMBL
      F1N199
      Related
      ENSBTAP00070001381.1, ENSBTAT00070002445.1
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials